INT70144

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Context Info
Confidence 0.63
First Reported 1997
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.15
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Sry) nucleus (Sry) enzyme binding (Sry)
DNA binding (Sry) transcription factor binding (Sry) cytoplasm (Sry)
Anatomy Link Frequency
testes 1
ND3 1
T cells 1
Sry (Mus musculus)
Pain Link Frequency Relevance Heat
Multiple sclerosis 121 79.80 Quite High
Chronic pancreatitis 2 76.56 Quite High
Inflammation 45 75.24 Quite High
Central nervous system 28 70.24 Quite High
alcohol 1 36.16 Quite Low
cytokine 23 5.00 Very Low Very Low Very Low
imagery 22 5.00 Very Low Very Low Very Low
rheumatoid arthritis 17 5.00 Very Low Very Low Very Low
Demyelination 5 5.00 Very Low Very Low Very Low
Arthritis 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Salivary Gland Disease 2 92.92 High High
Autoimmune Disease 44 87.68 High High
Pancreatitis 3 86.80 High High
Sprains And Strains 30 80.40 Quite High
Multiple Sclerosis 221 79.80 Quite High
Disorders Of The Lacrimal System 1 75.92 Quite High
INFLAMMATION 47 75.24 Quite High
Anaplastic Astrocytoma 6 61.60 Quite High
Disease 122 54.76 Quite High
Cancer 38 52.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In male mammals, the Y-linked gene Sry is expressed in cells of the undifferentiated gonadal ridges to cause them to differentiate into Sertoli cells, which begins the differentiation of the testes [219].
Gene_expression (expressed) of Sry in testes
1) Confidence 0.63 Published 2011 Journal Biol Sex Differ Section Body Doc Link PMC3022636 Disease Relevance 0.62 Pain Relevance 0.21
Sequence analysis of complementarity-determining region 3 (CDR3) of the most prominent TCR Vbeta gene family expressed in these cells, Vbeta1, showed oligoclonal expansion of infiltrating T cells in both organs.
Gene_expression (expressed) of complementarity-determining region 3 in T cells
2) Confidence 0.19 Published 1997 Journal J. Immunol. Section Abstract Doc Link 9200482 Disease Relevance 0.41 Pain Relevance 0.08
Amplified products of P53short, P53long, ND3, and SRY loci were run on a gel: 5 ?
Gene_expression (products) of SRY in ND3
3) Confidence 0.11 Published 2008 Journal BMC Biotechnol Section Body Doc Link PMC2266725 Disease Relevance 0 Pain Relevance 0
Putative binding sites for several known transcription factors, namely Sp1, E2F, CdxA, GATA, c-Ets, HSF2, Ik2, USF and SRY are found in the upstream region [28].
Gene_expression (found) of SRY
4) Confidence 0.05 Published 2008 Journal Current Genomics Section Body Doc Link PMC2691673 Disease Relevance 0.11 Pain Relevance 0

General Comments

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