INT70148

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.14
First Reported 1997
Last Reported 1997
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 1.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Acot1) endoplasmic reticulum (Drd1a) intracellular (Drd1a)
lipid metabolic process (Acot1) cytoplasm (Acot1) signal transducer activity (Drd1a)
Drd1a (Rattus norvegicus)
Acot1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 14 100.00 Very High Very High Very High
agonist 14 99.96 Very High Very High Very High
antagonist 14 98.98 Very High Very High Very High
tetrodotoxin 2 80.04 Quite High
substance P 2 25.00 Low Low

|}

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Among the 5-HT agents studied, only the 5-HT2A receptor antagonists ketanserin and ritanserin were able to reduce the ACh release induced by dopamine D1 receptor stimulation.
dopamine D1 receptor Positive_regulation (induced) of Localization (release) of ACh associated with dopamine and antagonist
1) Confidence 0.14 Published 1997 Journal Brain Res. Section Abstract Doc Link 9200494 Disease Relevance 0 Pain Relevance 0.85
GR 82334, a NK1 receptor antagonist, blocked not only the effect of [Sar9, met(O2)11]SP but also the release of ACh induced by the D1 receptor agonist SKF 38393.
D1 receptor Positive_regulation (induced) of Localization (release) of ACh associated with antagonist and agonist
2) Confidence 0.14 Published 1997 Journal Brain Res. Section Abstract Doc Link 9200494 Disease Relevance 0 Pain Relevance 0.85

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox