INT70156

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Context Info
Confidence 0.15
First Reported 1997
Last Reported 2000
Negated 1
Speculated 0
Reported most in Title
Documents 2
Total Number 2
Disease Relevance 0.79
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Casp1) cell death (Casp1) extracellular region (Casp1)
nucleus (Casp1) intracellular (Casp1) protein complex (Casp1)
Anatomy Link Frequency
astrocyte 1
Casp1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 2 99.92 Very High Very High Very High
opioid receptor 4 99.12 Very High Very High Very High
Opioid 6 96.32 Very High Very High Very High
cINOD 1 62.60 Quite High
Hippocampus 1 46.52 Quite Low
cytokine 2 36.40 Quite Low
Disease Link Frequency Relevance Heat
Apoptosis 10 99.22 Very High Very High Very High
Injury 1 64.52 Quite High
INFLAMMATION 1 62.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Z-VAD-FMK, a caspase inhibitor, inhibited both the increase in caspase-3-like protease activity and apoptosis in IND-treated RGM1 cells but did not affect caspase-1-like protease activity or mitochondrial cytochrome c release.
Neg (not) Regulation (affect) of caspase-1-like associated with apoptosis
1) Confidence 0.15 Published 2000 Journal Proc. Soc. Exp. Biol. Med. Section Abstract Doc Link 10806417 Disease Relevance 0.79 Pain Relevance 0.06
The interleukin-1beta-mediated regulation of proenkephalin and opioid receptor messenger RNA in primary astrocyte-enriched cultures.
Regulation (regulation) of interleukin-1beta-mediated in astrocyte associated with enkephalin and opioid receptor
2) Confidence 0.07 Published 1997 Journal Neuroscience Section Title Doc Link 9200734 Disease Relevance 0 Pain Relevance 0.64

General Comments

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