INT70216

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.78
First Reported 1997
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 8
Total Number 8
Disease Relevance 4.81
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (HSPB1) cell death (HSPB1) plasma membrane (HSPB1)
cytoskeleton (HSPB1) nucleus (HSPB1) intracellular (HSPB1)
Anatomy Link Frequency
temporomandibular joint 2
endometrium 1
HSPB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Snapping jaw 8 99.56 Very High Very High Very High
endometriosis 2 50.00 Quite Low
Dismenorea 2 50.00 Quite Low
Enkephalin 2 5.00 Very Low Very Low Very Low
substance P 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
nud 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 14 100.00 Very High Very High Very High
Cancer 244 99.98 Very High Very High Very High
Prostate Cancer 52 99.98 Very High Very High Very High
Temporomandibular Joint Syndrome 4 99.56 Very High Very High Very High
Metaplasia 4 95.64 Very High Very High Very High
Stress 4 94.24 High High
Temporomandibular Joint Disorders 4 79.20 Quite High
Metastasis 54 71.56 Quite High
Dysmenorrhea 2 70.56 Quite High
Endometriosis (extended) 3 69.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
HSP27 was weakly expressed in normal TMJ discs and highly up-regulated in discs of patients showing new vessel formation and chondroid metaplasia.
Gene_expression (expressed) of HSP27 associated with metaplasia
1) Confidence 0.78 Published 2002 Journal J Craniofac Surg Section Abstract Doc Link 12218804 Disease Relevance 0.50 Pain Relevance 0.15
Expression of heat shock protein 27 (HSP27) in human temporomandibular joint discs of patients with internal derangement.
Gene_expression (Expression) of HSP27 in temporomandibular joint associated with snapping jaw and shock
2) Confidence 0.78 Published 2002 Journal J Craniofac Surg Section Title Doc Link 12218804 Disease Relevance 0.55 Pain Relevance 0.17
This different pattern of HSP27 immunostaining in human TMJ discs detected in the authors' specimens suggests that the expression of this small HSP is functionally modulated.
Gene_expression (expression) of HSP27
3) Confidence 0.78 Published 2002 Journal J Craniofac Surg Section Abstract Doc Link 12218804 Disease Relevance 0.36 Pain Relevance 0.14
Expression of heat shock protein 27 (HSP27) in human temporomandibular joint discs of patients with internal derangement.
Gene_expression (Expression) of heat shock protein 27 in temporomandibular joint associated with snapping jaw and shock
4) Confidence 0.78 Published 2002 Journal J Craniofac Surg Section Title Doc Link 12218804 Disease Relevance 0.55 Pain Relevance 0.17
RESULT(S): Significantly increased expression of heat shock protein 27 was noted in eutopic endometrium from patients with endometriosis and adenomyosis as compared with controls, regardless of the menstrual phase.
Gene_expression (expression) of heat shock protein 27 in endometrium
5) Confidence 0.76 Published 1997 Journal Fertil. Steril. Section Body Doc Link 9207579 Disease Relevance 0.14 Pain Relevance 0
Letrozole, but not tamoxifen, significantly reduced the expression of estrogen-regulated proteins PgR and TFF1 [38].
Gene_expression (expression) of estrogen-regulated
6) Confidence 0.75 Published 2007 Journal Breast Cancer Res Treat Section Body Doc Link PMC2001223 Disease Relevance 0.38 Pain Relevance 0
Prostate cancer expression of Hsp27 has been linked to poor outcome by Cornford et al. [24] and therefore, cancer expression of either CD10 or Hsp27 appears to be both associated with a poor prognosis.
Gene_expression (expression) of Hsp27 associated with cancer and prostate cancer
7) Confidence 0.24 Published 2007 Journal BMC Urol Section Body Doc Link PMC1829163 Disease Relevance 1.22 Pain Relevance 0
Prostate cancer expression of Hsp27 has been linked to poor outcome by Cornford et al. [24] and therefore, cancer expression of either CD10 or Hsp27 appears to be both associated with a poor prognosis.
Gene_expression (expression) of Hsp27 associated with cancer and prostate cancer
8) Confidence 0.24 Published 2007 Journal BMC Urol Section Body Doc Link PMC1829163 Disease Relevance 1.10 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox