INT703

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Context Info
Confidence 0.70
First Reported 1977
Last Reported 2010
Negated 7
Speculated 2
Reported most in Abstract
Documents 177
Total Number 179
Disease Relevance 127.09
Pain Relevance 27.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Pth) extracellular region (Pth) cellular_component (Pth)
Anatomy Link Frequency
parathyroid 90
plasma 9
blood 5
spine 3
femur 2
Pth (Rattus norvegicus)
Pain Link Frequency Relevance Heat
headache 62 100.00 Very High Very High Very High
adenocard 2 100.00 Very High Very High Very High
halothane 24 99.98 Very High Very High Very High
pruritus 34 99.92 Very High Very High Very High
isoflurane 16 99.76 Very High Very High Very High
agonist 12 99.76 Very High Very High Very High
Pain 205 99.44 Very High Very High Very High
antagonist 12 99.36 Very High Very High Very High
ketamine 31 99.24 Very High Very High Very High
backache 55 99.08 Very High Very High Very High
Disease Link Frequency Relevance Heat
Headache 64 100.00 Very High Very High Very High
Hypersensitivity 34 100.00 Very High Very High Very High
Hypercalcemia 819 99.96 Very High Very High Very High
Chronic Renal Failure 250 99.96 Very High Very High Very High
Hydronephrosis 3 99.96 Very High Very High Very High
Osteoporosis 496 99.92 Very High Very High Very High
Disease 164 99.92 Very High Very High Very High
Rickets 58 99.92 Very High Very High Very High
Pruritus 46 99.92 Very High Very High Very High
Decapitation 4 99.92 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Halothane increased PTH in rat pups (74+/-8 pg/mL).
Positive_regulation (increased) of PTH associated with halothane
1) Confidence 0.70 Published 2002 Journal Endocrine Section Abstract Doc Link 12108514 Disease Relevance 0.69 Pain Relevance 0.49
Several anesthetics, but not diethyl ether, cause marked elevation of serum parathyroid hormone concentration in rats.
Positive_regulation (elevation) of parathyroid hormone in parathyroid
2) Confidence 0.70 Published 1995 Journal J. Bone Miner. Res. Section Title Doc Link 7502700 Disease Relevance 0.07 Pain Relevance 0.32
Both patients had a reduction in serum calcium level which was accompanied by a decline in the fasting urinary hydroxyproline/creatinine and calcium/creatinine ratios and a slight increase in parathyroid hormone (PTH) level.
Positive_regulation (increase) of PTH in parathyroid
3) Confidence 0.69 Published 1989 Journal J. Intern. Med. Section Abstract Doc Link 2918272 Disease Relevance 0.59 Pain Relevance 0.19
All four had, and continue to have, markedly elevated levels of parathyroid hormone (PTH).
Positive_regulation (elevated) of parathyroid hormone in parathyroid
4) Confidence 0.69 Published 1996 Journal Am. J. Kidney Dis. Section Abstract Doc Link 8957047 Disease Relevance 0.85 Pain Relevance 0.09
All four had, and continue to have, markedly elevated levels of parathyroid hormone (PTH).
Positive_regulation (elevated) of PTH in parathyroid
5) Confidence 0.69 Published 1996 Journal Am. J. Kidney Dis. Section Abstract Doc Link 8957047 Disease Relevance 0.85 Pain Relevance 0.09
Both patients had a reduction in serum calcium level which was accompanied by a decline in the fasting urinary hydroxyproline/creatinine and calcium/creatinine ratios and a slight increase in parathyroid hormone (PTH) level.
Positive_regulation (increase) of parathyroid hormone in parathyroid
6) Confidence 0.69 Published 1989 Journal J. Intern. Med. Section Abstract Doc Link 2918272 Disease Relevance 0.59 Pain Relevance 0.18
In primary hyperparathyroid patients, the identical procedure increased plasma parathyroid hormone levels from 206 +/- 104 pg/ml to 217 +/- 113 pg/ml (p = 0.12) and from 898 +/- 495 pg/ml to 1162 +/- 613 pg/ml (p = 0.07) in secondary hyperparathyroidism patients.
Positive_regulation (increased) of parathyroid hormone in parathyroid associated with hypercalcemia
7) Confidence 0.68 Published 2005 Journal Endocr. J. Section Abstract Doc Link 16410663 Disease Relevance 0.24 Pain Relevance 0.16
In the control group, tracheal intubation significantly increased plasma parathyroid hormone levels from 59 +/- 31 pg/ml to 91 +/- 40 pg/ml (mean +/- SD) (p<0.0003).
Positive_regulation (increased) of parathyroid hormone in plasma
8) Confidence 0.68 Published 2005 Journal Endocr. J. Section Abstract Doc Link 16410663 Disease Relevance 0.24 Pain Relevance 0.17
Bone formation markers increased markedly in the PTH group, but not in the combination therapy group.
Neg (not) Positive_regulation (increased) of PTH
9) Confidence 0.68 Published 2007 Journal Clinical Interventions in Aging Section Body Doc Link PMC2684083 Disease Relevance 0.10 Pain Relevance 0
However, there were increases in both cortical BMD (4.6%) and cortical volume (4.4%) in the PTH followed by ALN group.
Positive_regulation (increases) of PTH
10) Confidence 0.68 Published 2007 Journal Clinical Interventions in Aging Section Body Doc Link PMC2684083 Disease Relevance 0 Pain Relevance 0
Plasma levels of intact PTH were elevated to 278 pg/ml.
Positive_regulation (elevated) of PTH in Plasma
11) Confidence 0.68 Published 1997 Journal Hinyokika Kiyo Section Abstract Doc Link 9488943 Disease Relevance 0.57 Pain Relevance 0.14
And also PTH level was increased in hormonal assay when compared to that of cat reference range.
Positive_regulation (increased) of PTH
12) Confidence 0.68 Published 2004 Journal J. Vet. Med. Sci. Section Abstract Doc Link 15187368 Disease Relevance 0.50 Pain Relevance 0.13
Parathyroid hormone levels assessed with the radioimmunoassay method were elevated in all patients, and results of ultrasound of the neck, done in seven patients, revealed hyperplastic glands in six patients and normal glands in one patient.
Positive_regulation (elevated) of Parathyroid hormone in glands associated with hyperplasia
13) Confidence 0.68 Published 1988 Journal Surg Gynecol Obstet Section Abstract Doc Link 3381185 Disease Relevance 0.74 Pain Relevance 0.22
Ca, P and vitamin D were at lower limit of normal, ALP, Mg and PTH were increased in her laboratory tests.
Positive_regulation (increased) of PTH
14) Confidence 0.68 Published 2007 Journal Rheumatol. Int. Section Abstract Doc Link 17171347 Disease Relevance 0.68 Pain Relevance 0.10
Although it is difficult to diagnose preoperatively, there should be an increased index of suspicion in those hyperparathyroid patients with palpable neck masses, profound hypercalcemia (greater than 14 mg/100 ml), marked increase in the parathyroid hormone level to greater than twice normal, and significant metabolic complications.
Positive_regulation (increase) of parathyroid hormone in parathyroid associated with hypercalcemia
15) Confidence 0.67 Published 1985 Journal Am. J. Surg. Section Abstract Doc Link 3985291 Disease Relevance 1.02 Pain Relevance 0
Significant elevations of the parathyroid hormone level were noted with values two to three times normal.
Positive_regulation (elevations) of parathyroid hormone in parathyroid
16) Confidence 0.67 Published 1985 Journal Am. J. Surg. Section Abstract Doc Link 3985291 Disease Relevance 0.61 Pain Relevance 0.08
Laboratory data revealed markedly elevated serum calcium, low phosphorus, and elevated parathyroid hormone.
Positive_regulation (elevated) of parathyroid hormone in parathyroid
17) Confidence 0.67 Published 1985 Journal Clin Pediatr (Phila) Section Abstract Doc Link 3995865 Disease Relevance 0.55 Pain Relevance 0.09
Patients with either bone syndrome may present with hypercalcemia, elevations in parathyroid hormone levels, bone pain, fractures, and radiographic evidence of subperiosteal resorption.
Positive_regulation (elevations) of parathyroid hormone in parathyroid associated with pain, hypercalcemia and bone cancer
18) Confidence 0.67 Published 1986 Journal Semin. Nephrol. Section Abstract Doc Link 3299591 Disease Relevance 1.45 Pain Relevance 0.10
However, their values, were decreased gradually with the elevation of parathyroid hormone level.
Positive_regulation (elevation) of parathyroid hormone in parathyroid
19) Confidence 0.67 Published 1994 Journal Hinyokika Kiyo Section Abstract Doc Link 8191970 Disease Relevance 0.42 Pain Relevance 0.14
Other useful indications for operation include a marked elevation of the parathyroid hormone level and the elevation of the calcium x phosphate product over 70.
Positive_regulation (elevation) of parathyroid hormone in parathyroid
20) Confidence 0.67 Published 1995 Journal Surg. Clin. North Am. Section Abstract Doc Link 7747253 Disease Relevance 0.44 Pain Relevance 0.15

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