INT70404

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Context Info
Confidence 0.02
First Reported 1997
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 0
Pain Relevance 1.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mRNA binding (Ddx5) nucleolus (Ddx5) nucleus (Ddx5)
enzyme binding (Ddx5)
Ddx5 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
substance P 8 100.00 Very High Very High Very High
Enkephalin 10 98.96 Very High Very High Very High
Nucleus accumbens 2 94.44 High High
Neuropeptide 14 87.96 High High
agonist 6 79.52 Quite High
antagonist 4 76.72 Quite High
Dopamine 2 72.96 Quite High
projection neuron 2 68.48 Quite High
drug abuse 2 58.64 Quite High
Disease Link Frequency Relevance Heat
Drug Dependence 2 5.00 Very Low Very Low Very Low
Psychosis 2 5.00 Very Low Very Low Very Low
Parkinson's Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, it suppressed the increase in prodynorphin and substance P mRNA expression induced by methamphetamine.
Positive_regulation (induced) of Gene_expression (expression) of P mRNA associated with substance p
1) Confidence 0.02 Published 2003 Journal Eur. J. Neurosci. Section Abstract Doc Link 12542667 Disease Relevance 0 Pain Relevance 0.62
In contrast, it suppressed the increase in prodynorphin and substance P mRNA expression induced by methamphetamine.
Positive_regulation (increase) of Gene_expression (expression) of P mRNA associated with substance p
2) Confidence 0.02 Published 2003 Journal Eur. J. Neurosci. Section Abstract Doc Link 12542667 Disease Relevance 0 Pain Relevance 0.62
As reported previously, the unilateral dopaminergic lesion induced a significant and homogeneous decrease in striatal substance P mRNA expression and a marked increase in enkephalin mRNA expression in the ipsilateral neostriatum which was more pronounced in the dorsolateral than ventromedial part of the structure.
Positive_regulation (induced) of Gene_expression (expression) of P mRNA associated with enkephalin and substance p
3) Confidence 0.01 Published 1997 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 9221930 Disease Relevance 0 Pain Relevance 0.38

General Comments

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