INT70449

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Context Info
Confidence 0.36
First Reported 1997
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 8
Disease Relevance 5.10
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (SLC4A1) transmembrane transport (SLC4A1)
Anatomy Link Frequency
AE-1 2
AE-2 2
fossa 1
smooth muscle 1
A549 1
SLC4A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
palliative 1 72.64 Quite High
Angina 1 71.20 Quite High
methotrexate 12 62.80 Quite High
vincristine 12 57.68 Quite High
Inflammation 2 47.44 Quite Low
Pain 4 46.40 Quite Low
Analgesic 1 25.00 Low Low
cva 5 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
headache 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 178 100.00 Very High Very High Very High
Metastasis 42 97.98 Very High Very High Very High
Malignant Fibrous Histiocytoma 5 93.28 High High
Reprotox - General 1 152 92.56 High High
Malignant Neoplastic Disease 30 90.40 High High
Endometrial Cancer 24 87.28 High High
Lung Cancer 6 87.20 High High
Skin Cancer 24 82.16 Quite High
Necrosis 8 77.84 Quite High
Myocardial Infarction 1 74.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The Ki-67 index (MIB-1) was >50%, but other markers such as cytokeratin AE1/AE3, smooth muscle actin, S-100 protein, CD34, and CD45 were negative.
AE1 Binding (cytokeratin) of in smooth muscle
1) Confidence 0.36 Published 2008 Journal General thoracic and cardiovascular surgery Section Abstract Doc Link 19085056 Disease Relevance 0.83 Pain Relevance 0.07
Additionally, a subpopulation of cells in second passage cultures was immunoreactive to the anti-human cytokeratin antibody (AE1/AE3), which recognizes a wide range of human cytokeratins (Moll's designation 1–8, 10, 13–16, 19) [26].
AE1 Binding (recognizes) of
2) Confidence 0.35 Published 2005 Journal Cerebrospinal Fluid Res Section Body Doc Link PMC1285366 Disease Relevance 0.06 Pain Relevance 0
The metastasis from the right temporal fossa was characterized by a strong E-cadherin membrane staining and strong AE1/AE3 reactivity in the bulk of the tissue.
AE1 Binding (reactivity) of in fossa associated with metastasis
3) Confidence 0.35 Published 2010 Journal BMC Clin Pathol Section Body Doc Link PMC2829523 Disease Relevance 0.94 Pain Relevance 0.07
-hCG) (Figure 3) and cytokeratins (AE-1, AE-2) and negative for octamer binding transcription factor (OCT)-3/4, ?
AE-1 Binding (cytokeratins) of in AE-2
4) Confidence 0.16 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC3002375 Disease Relevance 0.65 Pain Relevance 0.06
-hCG) (Figure 3) and cytokeratins (AE-1, AE-2) and negative for octamer binding transcription factor (OCT)-3/4, ?
AE-1 Binding (binding) of in AE-2
5) Confidence 0.16 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC3002375 Disease Relevance 0.66 Pain Relevance 0.06
-hCG) (Figure 3) and cytokeratins (AE-1, AE-2) and negative for octamer binding transcription factor (OCT)-3/4, ?
AE-1 Binding (binding) of in AE-1
6) Confidence 0.06 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC3002375 Disease Relevance 0.66 Pain Relevance 0.06
-hCG) (Figure 3) and cytokeratins (AE-1, AE-2) and negative for octamer binding transcription factor (OCT)-3/4, ?
AE-1 Binding (cytokeratins) of in AE-1
7) Confidence 0.06 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC3002375 Disease Relevance 0.65 Pain Relevance 0.06
Using a whole-cell assay and nuclear and cytosolic radiobinding experiments with [3H]estradiol as tracer, we have found that SK-LU1, SW900, ChaGo-K-1, H441, H661, and A549 cells, as well as primary tumors, bind estrogen specifically.
SW900 Binding (bind) of in A549 associated with cancer
8) Confidence 0.00 Published 1997 Journal Am. J. Respir. Cell Mol. Biol. Section Abstract Doc Link 9224209 Disease Relevance 0.64 Pain Relevance 0

General Comments

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