INT70478

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Context Info
Confidence 0.33
First Reported 1997
Last Reported 1997
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.33
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (PIGA) biosynthetic process (PIGA) plasma membrane (HTR1F)
signal transducer activity (HTR1F)
HTR1F (Homo sapiens)
PIGA (Homo sapiens)
Pain Link Frequency Relevance Heat
Sumatriptan 2 97.56 Very High Very High Very High
Migraine 5 80.68 Quite High
Serotonin 1 72.52 Quite High
trigeminal ganglion 1 59.68 Quite High
neuropeptide release 1 51.20 Quite High
Inflammation 1 42.08 Quite Low
dorsal root ganglion 1 40.96 Quite Low
Pain 1 25.00 Low Low
agonist 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Headache 5 80.68 Quite High
Ganglion Cysts 2 58.80 Quite High
Neurogenic Inflammation 1 42.96 Quite Low
Nociception 1 27.52 Quite Low
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The cloned guinea pig receptor displayed typical 5-HT1F receptor pharmacology with the following rank order of binding affinities: 5-HT > sumatriptan > 1-NP = DHE > alpha-methyl 5-HT > metergoline > methiothepin > 5-CT.
5-HT1F Binding (pharmacology) of pig receptor associated with sumatriptan
1) Confidence 0.33 Published 1997 Journal Neuropharmacology Section Abstract Doc Link 9225282 Disease Relevance 0.33 Pain Relevance 0.52

General Comments

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