INT70590

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Context Info
Confidence 0.08
First Reported 1997
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.44
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
astrocyte 1
Olr1868 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
tetrodotoxin 1 84.08 Quite High
allodynia 1 72.44 Quite High
Peripheral nerve injury 1 71.28 Quite High
Inflammation 1 65.52 Quite High
agonist 1 64.80 Quite High
Lasting pain 1 53.28 Quite High
chemokine 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Death 1 85.48 High High
Injury 1 77.12 Quite High
Neuropathic Pain 1 72.44 Quite High
Nervous System Injury 2 71.28 Quite High
INFLAMMATION 1 65.52 Quite High
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Application of the full-length peptide (GAL1-29) or of the N-terminal fragment GAL1-16 produced reversible membrane hyperpolarization with an IC50 near 10 nM.
Gene_expression (produced) of GAL1-29
1) Confidence 0.08 Published 1997 Journal J. Neurosci. Section Abstract Doc Link 9236216 Disease Relevance 0 Pain Relevance 0.12
Minocycline significantly reduced microglial migration to cellular debris, astrocyte-conditioned medium, ADP, and algesic mediators and significantly reduced the expression of CD29 (beta(1)-integrin) but not CD18 (beta(2)-integrin).
Gene_expression (expression) of CD29 in astrocyte
2) Confidence 0.02 Published 2007 Journal J. Neurochem. Section Abstract Doc Link 17868321 Disease Relevance 0.44 Pain Relevance 0.19

General Comments

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