INT70712

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Context Info
Confidence 0.06
First Reported 1997
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 6
Disease Relevance 2.02
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
adipocytes 1
heart 1
Apo (Mus musculus)
Pain Link Frequency Relevance Heat
noradrenaline 14 82.08 Quite High
Angina 1 65.44 Quite High
Catecholamine 12 63.84 Quite High
alcohol 1 25.00 Low Low
peptic ulcer disease 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 6 100.00 Very High Very High Very High
Obesity 83 99.28 Very High Very High Very High
Coronary Artery Disease 7 98.80 Very High Very High Very High
Sprains And Strains 284 88.00 High High
Myocardial Infarction 1 69.92 Quite High
Cv General 3 Under Development 1 65.44 Quite High
Repression 12 64.96 Quite High
Disease 9 52.32 Quite High
Atherosclerosis 2 42.96 Quite Low
Nicotine Addiction 2 36.56 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Rather, in H. pylori it is perhaps more plausible that both iron-bound and apo-Fur recognize unique DNA structures that are required for proper regulation of their target genes.
apo Binding (recognize) of
1) Confidence 0.06 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2671405 Disease Relevance 0 Pain Relevance 0
The objective of the present study was to examine the possible associations between low molecular weight (LMW) apolipoprotein(a) (apo(a)) isoforms (F,B,S1,S2) and coronary heart disease (CHD).
apo Binding (associations) of in heart associated with coronary artery disease and disorder of lipid metabolism
2) Confidence 0.05 Published 1997 Journal Atherosclerosis Section Abstract Doc Link 9247362 Disease Relevance 0.63 Pain Relevance 0.07
As Ernst, et al. suggested, a weak affinity between apo-Fur and the sodB promoter makes physiological sense, as SodB is the only defense H. pylori has against superoxide radical damage [1], [10].
apo Binding (affinity) of
3) Confidence 0.04 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2671405 Disease Relevance 0.27 Pain Relevance 0
To assay the binding of apo-Fur, we performed Electrophoretic Mobility Shift Assays (EMSAs) and competition studies for each sodB promoter (WT G27, “?
apo Binding (binding) of
4) Confidence 0.04 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2671405 Disease Relevance 0.27 Pain Relevance 0
There is no defined consensus sequence for apo-Fur binding given that the two promoters of the known apo-Fur regulated genes, pfr and sodB, share only minimal homology [1], [8].
apo Binding (binding) of
5) Confidence 0.04 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2671405 Disease Relevance 0.11 Pain Relevance 0
Since the LDL receptor (LDLR) is expressed on adipocytes [8], we investigated its role in the interaction between apoB100 lipoproteins and adipocytes by analyzing apoB100-only mice that expressed the LDLR (Ldlr+/+Apob100/100) or were LDLR-deficient (Ldlr?
apoB100 Binding (interaction) of in adipocytes associated with obesity
6) Confidence 0.01 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2582480 Disease Relevance 0.74 Pain Relevance 0.14

General Comments

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