INT70825

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Context Info
Confidence 0.70
First Reported 1997
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 1.71
Pain Relevance 1.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (NINJ1)
Anatomy Link Frequency
neurons 1
peripheral nerve 1
NINJ1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Hsan 13 99.84 Very High Very High Very High
dorsal root ganglion 4 98.88 Very High Very High Very High
Peripheral nerve injury 2 98.56 Very High Very High Very High
Disease Link Frequency Relevance Heat
Hereditary Sensory And Autonomic Neuropathies 13 99.84 Very High Very High Very High
Nervous System Injury 3 99.72 Very High Very High Very High
Ganglion Cysts 4 98.40 Very High Very High Very High
Adhesions 5 87.04 High High
Disease 1 25.00 Low Low
Dilated Cardiomyopathy 1 5.00 Very Low Very Low Very Low
Foot Deformities 1 5.00 Very Low Very Low Very Low
Carcinoma 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Ninjurin is a protein that is up-regulated in Schwann cells and neurons after peripheral nerve injury.
Positive_regulation (up-regulated) of Ninjurin in peripheral nerve associated with nervous system injury and peripheral nerve injury
1) Confidence 0.70 Published 1999 Journal Am. J. Med. Genet. Section Abstract Doc Link 10232753 Disease Relevance 0.46 Pain Relevance 0.42
Our results rule out a mutation in the translated region of the ninjurin gene as a cause of HSN type I and type II.
Positive_regulation (cause) of ninjurin associated with hsan
2) Confidence 0.50 Published 1999 Journal Am. J. Med. Genet. Section Abstract Doc Link 10232753 Disease Relevance 0.59 Pain Relevance 0.55
Ninjurin is a novel protein that is up-regulated after nerve injury both in dorsal root ganglion (DRG) neurons and in Schwann cells.
Positive_regulation (up-regulated) of Ninjurin in neurons associated with ganglion cysts, dorsal root ganglion and nervous system injury
3) Confidence 0.50 Published 1997 Journal J. Biol. Chem. Section Abstract Doc Link 9261151 Disease Relevance 0.66 Pain Relevance 0.14

General Comments

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