INT70916

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.02
First Reported 1997
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 13
Total Number 13
Disease Relevance 8.35
Pain Relevance 1.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
skin 1
Thim (Mus musculus)
Thim - N34S (3)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 117 99.98 Very High Very High Very High
Pain 9 86.64 High High
Neuritis 3 79.72 Quite High
cva 1 76.04 Quite High
Osteoarthritis 1 62.44 Quite High
Inflammation 6 43.72 Quite Low
fibrosis 14 42.72 Quite Low
headache 1 35.36 Quite Low
Paresthesia 1 27.04 Quite Low
Bile 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatitis 161 99.98 Very High Very High Very High
Disease 29 99.98 Very High Very High Very High
Diabetes Mellitus 14 99.98 Very High Very High Very High
Brachial Plexus Neuritis 10 99.98 Very High Very High Very High
Osteochondrodysplasias 3 99.98 Very High Very High Very High
Cancer 13 99.76 Very High Very High Very High
Deep Vein Thrombosis 1 99.40 Very High Very High Very High
Syndrome 5 99.28 Very High Very High Very High
Pancreatic Cancer 30 98.92 Very High Very High Very High
Heart Rate Under Development 13 98.84 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Partial HELLP syndrome in pregnancy complicated by recurrent deep vein thromboses and palmar skin lesions in a patient with prothrombin gene 20210a mutation and antiphospholipid antibodies: an unusual case.
mutation Binding (patient) of in skin associated with syndrome and deep vein thrombosis
1) Confidence 0.02 Published 2008 Journal Clin. Rheumatol. Section Title Doc Link 17610004 Disease Relevance 0.66 Pain Relevance 0.12
However, a false association of the mutant phenotype with the target gene due to the co-segregation of an off-target mutation is extremely unlikely.
mutation Binding (association) of
2) Confidence 0.01 Published 2005 Journal BMC Genomics Section Body Doc Link PMC1325271 Disease Relevance 0 Pain Relevance 0
Intrafamilial phenotypic diversity in multiple epiphyseal dysplasia associated with a COL9A2 mutation (EDM2).
mutation Binding (associated) of associated with osteochondrodysplasias
3) Confidence 0.00 Published 2006 Journal Clin. Rheumatol. Section Title Doc Link 16440132 Disease Relevance 0.36 Pain Relevance 0.10
Most laboratories have focused their studies on PRSS1 exons 2 and 3, and until now no unambiguous disease associated mutation has been identified in the other exons.
mutation Neg (no) Binding (associated) of associated with disease
4) Confidence 0.00 Published 2007 Journal Orphanet J Rare Dis Section Body Doc Link PMC1774562 Disease Relevance 0.57 Pain Relevance 0.22
Diabetes mellitus associated with mitochondrial tRNA mutation at position 3243(DM-Mt3243) is a new disease.
mutation Binding (associated) of associated with diabetes mellitus and disease
5) Confidence 0.00 Published 1997 Journal Mol. Aspects Med. Section Abstract Doc Link 9266520 Disease Relevance 0.93 Pain Relevance 0
Dysmorphic syndrome of hereditary neuralgic amyotrophy associated with a SEPT9 gene mutation--a family study.
mutation Binding (associated) of associated with syndrome and brachial plexus neuritis
6) Confidence 0.00 Published 2008 Journal Clin. Genet. Section Title Doc Link 18492087 Disease Relevance 1.64 Pain Relevance 0.21
LPL S447X mutation is associated with a higher risk of pancreatic calcification and steatorrhea than those previously known factors in HLP patients.


mutation Binding (associated) of
7) Confidence 0.00 Published 2009 Journal J. Clin. Gastroenterol. Section Body Doc Link 19034041 Disease Relevance 0 Pain Relevance 0
At a minimum, K-ras mutation is associated with the events that increase angiogenesis and it may potentiate or promote tumor angiogenesis.
mutation Binding (associated) of associated with cancer
8) Confidence 0.00 Published 2000 Journal Pancreas Section Abstract Doc Link 10766450 Disease Relevance 1.76 Pain Relevance 0.79
Chronic pancreatitis associated with an activation peptide mutation that facilitates trypsin activation.
mutation Binding (associated) of associated with chronic pancreatitis
9) Confidence 0.00 Published 2000 Journal Gastroenterology Section Title Doc Link 10930381 Disease Relevance 0.20 Pain Relevance 0.19
We report a case of pancreatic cancer associated with chronic calcifying pancreatitis in a patient with a homozygous N34S mutation in the SPINK1 gene.
mutation Binding (patient) of associated with pancreatitis and pancreatic cancer
10) Confidence 0.00 Published 2004 Journal Pancreas Section Abstract Doc Link 15084977 Disease Relevance 1.03 Pain Relevance 0
Although this case does not meet the classic criteria of hereditary pancreatitis, it does suggest that the SPINK1 N34S mutation may be associated with cancer development in patients with hereditary pancreatitis.
mutation (N34S) Binding (associated) of associated with cancer and pancreatitis
11) Confidence 0.00 Published 2004 Journal Pancreas Section Abstract Doc Link 15084977 Disease Relevance 1.22 Pain Relevance 0.09
RESULTS: Alternative splicing was not associated with the N34S mutation.
mutation (N34S) Binding (associated) of
12) Confidence 0.00 Published 2007 Journal Pancreas Section Body Doc Link 17446841 Disease Relevance 0 Pain Relevance 0
CONCLUSIONS: Splicing mutation might represent a mechanism for SPINK1-associated CP, but the N34S mutation is not associated with alternative splicing.


mutation (N34S) Binding (associated) of
13) Confidence 0.00 Published 2007 Journal Pancreas Section Body Doc Link 17446841 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox