INT71046

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Context Info
Confidence 0.78
First Reported 1997
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 5
Disease Relevance 1.38
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CYP19A1) small molecule metabolic process (CYP19A1) endoplasmic reticulum (CYP19A1)
cytoplasm (CYP19A1)
Anatomy Link Frequency
endometrium 1
CYP19A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dismenorea 6 97.68 Very High Very High Very High
endometriosis 29 92.72 High High
antagonist 176 5.00 Very Low Very Low Very Low
agonist 136 5.00 Very Low Very Low Very Low
corticosteroid 32 5.00 Very Low Very Low Very Low
dexamethasone 20 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
ischemia 4 5.00 Very Low Very Low Very Low
Bioavailability 4 5.00 Very Low Very Low Very Low
backache 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Endometriosis 15 98.40 Very High Very High Very High
Disease 5 94.40 High High
Ovarian Hyperstimulation Syndrome 44 83.16 Quite High
Polycystic Ovary Syndrome 48 72.96 Quite High
Reprotox - General 3 152 71.28 Quite High
Reprotox - General 1 5 69.44 Quite High
Sexual Infantilism 8 68.48 Quite High
Obesity 44 41.68 Quite Low
Malignant Neoplastic Disease 4 37.44 Quite Low
Breast Cancer 20 36.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
P450arom was immunohistochemically localized in the cytoplasm of glandular cells of endometriotic and adenomyotic tissues, and of eutopic endometrium from patients with the respective diseases, whereas estrogen receptors and progesterone receptors were localized in the nuclei of the glandular cells and stroma.
Localization (localized) of P450arom in endometrium associated with endometriosis, dismenorea and disease
1) Confidence 0.78 Published 1997 Journal Biol. Reprod. Section Abstract Doc Link 9282984 Disease Relevance 0.88 Pain Relevance 0.48
Aromatase enzyme deficiency and the use of aromatase inhibitors
Localization (use) of Aromatase enzyme
2) Confidence 0.58 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1266397 Disease Relevance 0.14 Pain Relevance 0
This would have a tremendous economic impact on the practice of assisted reproduction, as well as cost of health care for multiple gestation worldwide.

1.2 Outline of the use of aromatase inhibitors for ovarian stimulation

Localization (use) of aromatase
3) Confidence 0.58 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1266397 Disease Relevance 0.08 Pain Relevance 0
Aromatase enzyme deficiency and the use of aromatase inhibitors
Localization (use) of aromatase
4) Confidence 0.58 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1266397 Disease Relevance 0.14 Pain Relevance 0
1.2.2 Adjunct use of aromatase inhibitors for ovarian stimulation
Localization (use) of aromatase
5) Confidence 0.58 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1266397 Disease Relevance 0.14 Pain Relevance 0

General Comments

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