INT7106

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Context Info
Confidence 0.27
First Reported 1984
Last Reported 2010
Negated 3
Speculated 1
Reported most in Abstract
Documents 8
Total Number 9
Disease Relevance 5.24
Pain Relevance 2.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
spinal 2
artery 1
pad (Mus musculus)
Pain Link Frequency Relevance Heat
GABAergic 5 100.00 Very High Very High Very High
narcan 14 98.44 Very High Very High Very High
Restless leg syndrome 40 95.68 Very High Very High Very High
gABA 4 84.36 Quite High
Dorsal column 2 80.96 Quite High
Pain 23 76.00 Quite High
Spinal cord 4 75.00 Quite High
Morphine 4 75.00 Quite High
depression 2 55.60 Quite High
medulla 1 51.36 Quite High
Disease Link Frequency Relevance Heat
Peripheral Arterial Disease 242 100.00 Very High Very High Very High
Paralysis 1 99.78 Very High Very High Very High
Cardiovascular Disease 16 99.40 Very High Very High Very High
Disease 16 98.64 Very High Very High Very High
Increased Venous Pressure Under Development 69 97.20 Very High Very High Very High
Obesity 1 90.48 High High
Pain 18 76.00 Quite High
Hyperlipidemia 6 72.08 Quite High
Myocardial Infarction 24 59.44 Quite High
Depression 2 55.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Chelation therapy has been demonstrated to be ineffective in the therapy of PAD (Ernst 1997).
Regulation (ineffective) of PAD associated with peripheral arterial disease
1) Confidence 0.27 Published 2007 Journal Clinical Interventions in Aging Section Body Doc Link PMC2686340 Disease Relevance 0.96 Pain Relevance 0.55
The Minnesota Regional Peripheral Arterial Disease Screening Program was designed to define the efficacy of community PAD detection efforts, to assess the disease-specific and health-related morbidity, to assess PAD awareness rates, and to determine the magnitude of atherosclerosis disease risk factors and the intensity of their management.
Regulation (efficacy) of PAD associated with increased venous pressure under development, disease and peripheral arterial disease
2) Confidence 0.23 Published 2001 Journal Vasc Med Section Abstract Doc Link 11530970 Disease Relevance 0.84 Pain Relevance 0.07
The purpose of the present series of experiments was to analyze, in anesthetized and paralyzed cats, the effects of (-)-baclofen and picrotoxin on the primary afferent depolarization (PAD) generated in single Ib afferent fibers by either intraspinal microstimulation or stimulation of the segmental and descending pathways.
Spec (analyze) Regulation (effects) of PAD associated with peripheral arterial disease and paralysis
3) Confidence 0.23 Published 1992 Journal Exp Brain Res Section Abstract Doc Link 1338717 Disease Relevance 0.47 Pain Relevance 0.05
It was demonstrated that the outcome of the therapy was not dependent on the supine or sitting tcpO2, the malleolar artery pressure, the patient's age or sex, the duration of PAD, the number or kind of concomitant diseases, the patient's general condition, the localization and number of vascular occlusions, the kind of prior therapy, or the number of previous amputations, although differences in some of the parameters, while clinically irrelevant, were found to be statistically significant.
Neg (not) Regulation (dependent) of PAD in artery
4) Confidence 0.20 Published 2005 Journal VASA Section Body Doc Link 15968891 Disease Relevance 0 Pain Relevance 0
As shown in Fig. 1, the PAD prevalence estimate was profoundly affected by the mode of ABI calculation.
Regulation (affected) of PAD associated with peripheral arterial disease
5) Confidence 0.17 Published 2007 Journal BMC Public Health Section Body Doc Link PMC1950873 Disease Relevance 0.59 Pain Relevance 0.10
We studied the feasibility of its assessment in a clinical setting, compared values from PAD and healthy participants, and identified factors affecting rmVO( 2) in PAD.
Regulation (affecting) of PAD associated with peripheral arterial disease
6) Confidence 0.12 Published 2010 Journal Angiology Section Abstract Doc Link 20395235 Disease Relevance 0.82 Pain Relevance 0.07
Intravenously administered naloxone, in doses known to enhance spinal monosynaptic excitation in the cat, had no effect on GABAergic PAD and little or no effect on Ia termination threshold.
Neg (little) Regulation (effect) of PAD in spinal associated with gabaergic, narcan and peripheral arterial disease
7) Confidence 0.04 Published 1984 Journal Brain Res. Section Abstract Doc Link 6744025 Disease Relevance 0.36 Pain Relevance 0.66
Intravenously administered naloxone, in doses known to enhance spinal monosynaptic excitation in the cat, had no effect on GABAergic PAD and little or no effect on Ia termination threshold.
Neg (no) Regulation (effect) of PAD in spinal associated with gabaergic, narcan and peripheral arterial disease
8) Confidence 0.02 Published 1984 Journal Brain Res. Section Abstract Doc Link 6744025 Disease Relevance 0.36 Pain Relevance 0.66
The purpose of this review is to summarize available evidence associated with ABI methodology variances, ABI usage in the treatment of PAD, and ABI efficacy in predicting cardiovascular disease.
Regulation (efficacy) of PAD associated with cardiovascular disease and peripheral arterial disease
9) Confidence 0.01 Published 2008 Journal Current Cardiology Reviews Section Abstract Doc Link PMC2779349 Disease Relevance 0.84 Pain Relevance 0

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