INT71070

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Context Info
Confidence 0.26
First Reported 1997
Last Reported 1997
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cck) extracellular region (Cck) plasma membrane (Oprl1)
signal transducer activity (Oprl1)
Anatomy Link Frequency
ventromedial hypothalamic nucleus 3
Oprl1 (Rattus norvegicus)
Cck (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Cholecystokinin 12 100.00 Very High Very High Very High
opiate 8 100.00 Very High Very High Very High
Endogenous opioid 4 93.12 High High
Neuropeptide 2 80.64 Quite High
Limbic system 3 78.48 Quite High
antagonist 4 75.44 Quite High
Enkephalin 4 75.00 Quite High
amygdala 3 57.96 Quite High
substance P 4 31.64 Quite Low
Central grey 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Activation of the mu-opiate receptor, however, may facilitate cholecystokinin messenger RNA expression in the bed nucleus of the stria terminalis and preprotachykinin messenger RNA expression in the ventromedial hypothalamic nucleus.
Positive_regulation (Activation) of mu-opiate receptor in ventromedial hypothalamic nucleus Spec (may) Positive_regulation (facilitate) of Gene_expression (expression) of cholecystokinin in ventromedial hypothalamic nucleus associated with opiate and cholecystokinin
1) Confidence 0.26 Published 1997 Journal Neuroscience Section Abstract Doc Link 9284350 Disease Relevance 0 Pain Relevance 1.24

General Comments

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