INT71097

Context Info Confidence 0.73 First Reported 1997 Last Reported 2003 Negated 0 Speculated 0 Reported most in Abstract Documents 2 Total Number 3 Disease Relevance 0.27 Pain Relevance 0.10

Anatomy Link Frequency nerve 2 Nasal 1 Igha (Mus musculus)

Pain Link Frequency Relevance Heat anesthesia 3 96.04

Disease Link Frequency Relevance Heat Immunization 2 99.16 Vibrio Infection 1 91.84

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Nasal immunizations with GBS alone led to at least tenfold higher levels of specific IgA-antibodies to GBS in cervicovaginal secretions than with any other immunization.

Localization (secretions) of IgA in Nasal associated with immunization

1) Confidence 0.73 Published 1997 Journal Vaccine Section Abstract Doc Link 9286051 Disease Relevance 0.27 Pain Relevance 0.10

It can be concluded that IgA and other major submandibular proteins are secreted into glandular lumina in the absence of nerve stimulation.

Localization (secreted) of IgA in nerve

2) Confidence 0.48 Published 2003 Journal Exp. Physiol. Section Abstract Doc Link 12525850 Disease Relevance 0 Pain Relevance 0

In order to determine if immunoglobulin A (IgA) and salivary proteins are secreted in the absence of nerve stimulation, small volumes (< 2 microl) of saliva were consecutively collected from the submandibular duct of anaesthetised rats following rest pauses in order to sample the protein contents of the ductal system.

Localization (secreted) of IgA in nerve

3) Confidence 0.42 Published 2003 Journal Exp. Physiol. Section Abstract Doc Link 12525850 Disease Relevance 0 Pain Relevance 0

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