INT71212

Context Info Confidence 0.14 First Reported 1997 Last Reported 2008 Negated 0 Speculated 0 Reported most in Abstract Documents 2 Total Number 2 Disease Relevance 0.53 Pain Relevance 0.25

extracellular region (AKR1B10) cellular_component (AKR1B10) lysosome (AKR1B10)

Anatomy Link Frequency PVN 1 AKR1B10 (Homo sapiens)

Pain Link Frequency Relevance Heat Pain 2 92.12 Enkephalin 2 80.56

Disease Link Frequency Relevance Heat Mental Disorders 1 93.88 Pain 2 92.12 Stress 3 75.40 Myocardial Infarction 23 64.16 Death 5 5.00 Coma 2 5.00 Critical Illness 2 5.00 Sepsis 1 5.00 Chronic Disease 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The 81 long-term survivors reached a mean HSI of 0.77 (95% CI 0.70 to 0.85).

Positive_regulation (reached) of HSI

1) Confidence 0.14 Published 2008 Journal Crit Care Section Body Doc Link PMC2575575 Disease Relevance 0.38 Pain Relevance 0.17

In situ hybridization revealed that novelty or HSI elevated levels of PPE hnRNA and c-fos mRNA in the PVN.

Positive_regulation (elevated) of HSI in PVN

2) Confidence 0.02 Published 1997 Journal Brain Res. Section Abstract Doc Link 9295199 Disease Relevance 0.15 Pain Relevance 0.08

General Comments

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