INT71221

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Context Info
Confidence 0.55
First Reported 1997
Last Reported 1997
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.81
Pain Relevance 1.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Prkar1b) signal transduction (Prkar1b) cytoplasm (Prkar1b)
Anatomy Link Frequency
dorsal root ganglion 1
Prkar1b (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 5 99.44 Very High Very High Very High
dorsal root ganglion 1 97.12 Very High Very High Very High
Inflammation 4 95.24 Very High Very High Very High
primary afferent fibers 1 90.32 High High
intrathecal 1 85.96 High High
qutenza 2 81.64 Quite High
Dorsal horn 1 76.00 Quite High
Neuropathic pain 1 75.00 Quite High
painful pain 1 75.00 Quite High
Lasting pain 1 73.32 Quite High
Disease Link Frequency Relevance Heat
Pain 6 99.44 Very High Very High Very High
Neuropathic Pain 2 99.20 Very High Very High Very High
Nervous System Injury 2 98.40 Very High Very High Very High
Nociception 4 96.68 Very High Very High Very High
Ganglion Cysts 1 96.64 Very High Very High Very High
Injury 3 95.88 Very High Very High Very High
INFLAMMATION 4 95.24 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because the RIbeta subunit is only present in the nervous system, including small diameter trkA receptor-positive dorsal root ganglion cells, we suggest that in inflammatory conditions, RIbeta PKA is specifically required for nociceptive processing in the terminals of small-diameter primary afferent fibers.
Gene_expression (present) of RIbeta in dorsal root ganglion associated with nociception, ganglion cysts, dorsal root ganglion, inflammation and primary afferent fibers
1) Confidence 0.55 Published 1997 Journal J. Neurosci. Section Abstract Doc Link 9295392 Disease Relevance 1.81 Pain Relevance 1.05

General Comments

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