INT71245

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Context Info
Confidence 0.21
First Reported 1997
Last Reported 1997
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.06
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Prkaca) nucleoplasm (Prkaca) mitochondrion (Prkaca)
Golgi apparatus (Prkaca) plasma membrane (Prkaca) nucleus (Prkaca)
Anatomy Link Frequency
cerebral cortex 4
Prkaca (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cerebral cortex 6 98.44 Very High Very High Very High
anesthesia 2 95.16 Very High Very High Very High
Disease Link Frequency Relevance Heat
Propionic Acidemia 2 59.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Taken together, these results suggest that MMA, at the same concentrations found in tissues of methylmalonic acidemic children, inhibits the in vitro activities of PKA, CaMKII and PP1 associated with the cytoskeletal fraction of the cerebral cortex of rats, a fact that may be involved with the pathogenesis of the neurological dysfunction characteristic of methylmalonic acidemia.
Negative_regulation (inhibits) of PKA Binding (associated) of in cerebral cortex associated with anesthesia and cerebral cortex
1) Confidence 0.21 Published 1997 Journal Brain Res. Section Abstract Doc Link 9296563 Disease Relevance 0 Pain Relevance 0.24
Taken together, these results demonstrate that PA inhibits the in vitro activities of PKA, CaMKII, and PP1 associated with the cytoskeletal fraction of the cerebral cortex of rats.
Negative_regulation (inhibits) of PKA Binding (associated) of in cerebral cortex associated with cerebral cortex
2) Confidence 0.20 Published 1997 Journal Exp. Neurol. Section Abstract Doc Link 9344549 Disease Relevance 0.06 Pain Relevance 0.17

General Comments

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