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Context Info
Confidence 0.44
First Reported 1997
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 3.59
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CCL11) extracellular space (CCL11) extracellular region (CCL11)
cell adhesion (CCL11) cytoskeleton organization (CCL11)
Anatomy Link Frequency
eosinophils 2
CCL11 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 1 98.68 Very High Very High Very High
fibrosis 5 91.04 High High
Inflammation 6 84.20 Quite High
chemokine 3 82.12 Quite High
pain pelvic 1 72.68 Quite High
cytokine 9 42.76 Quite Low
Crohn's disease 5 5.00 Very Low Very Low Very Low
Nerve growth factor 4 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Eosinophilia 3 99.64 Very High Very High Very High
Hypersensitivity 5 99.52 Very High Very High Very High
Eosinophilic Esophagitis 106 98.52 Very High Very High Very High
Disease 19 98.52 Very High Very High Very High
INFLAMMATION 7 98.48 Very High Very High Very High
Wound Healing 1 94.08 High High
Uterine Fibroids 6 93.16 High High
Fibrosis 7 91.04 High High
Parasitic Infection 3 87.68 High High
Asthma 2 86.68 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There was no consistent association between the presence of eosinophils and either IL-5 or eotaxin in smooth muscle cells, suggesting that mechanisms other than IL-5 or eotaxin production may account for the eosinophilia.
Spec (may) Regulation (account) of Gene_expression (production) of eotaxin in eosinophils associated with eosinophilia
1) Confidence 0.44 Published 2001 Journal Int. J. Gynecol. Pathol. Section Abstract Doc Link 11444199 Disease Relevance 1.69 Pain Relevance 0.12
Among the regulatory promoter elements potentially regulating eotaxin gene expression and/or mediating the effects of anti-inflammatory drugs we identified consensus sequences known to interact with nuclear factors like NF-IL6, AP-1, a NF-kappa-B like consensus sequence and gamma-interferon- as well as glucocorticoid response elements.
Regulation (regulating) of Gene_expression (expression) of eotaxin gene associated with inflammation and cinod
2) Confidence 0.43 Published 1997 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 9299399 Disease Relevance 0.70 Pain Relevance 0.18
Interestingly, we did not detect a difference in FGF and eotaxin expression in atopic (allergic) vs. non atopic EoE patients.
Regulation (difference) of Gene_expression (expression) of eotaxin associated with hypersensitivity and eosinophilic esophagitis
3) Confidence 0.09 Published 2010 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2976489 Disease Relevance 1.20 Pain Relevance 0.07

General Comments

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