INT71309

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Context Info
Confidence 0.21
First Reported 1997
Last Reported 1997
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.26
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Il1a, Nos2) extracellular space (Il1a, Nos2) aging (Nos2)
peroxisome (Nos2) intracellular (Nos2) cytoplasm (Nos2)
Anatomy Link Frequency
uterine 1
Il1a (Rattus norvegicus)
Nos2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dismenorea 2 100.00 Very High Very High Very High
cytokine 2 92.40 High High
Disease Link Frequency Relevance Heat
Dysmenorrhea 2 100.00 Very High Very High Very High
Rupture 2 89.76 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL-1 alpha administered intraperitoneally to rats induced an increase in the amount of mRNA encoding the macro-phage-type iNOS which was determined by reverse transcription-polymerase chain reaction.
IL-1 alpha Positive_regulation (increase) of iNOS
1) Confidence 0.21 Published 1997 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 9299442 Disease Relevance 0.09 Pain Relevance 0.12
These findings suggest that in women with PROM, amniotic IL-1 alpha may reduce uterine contractions, in part, by inducing of iNOS.
IL-1 alpha Positive_regulation (inducing) of iNOS in uterine associated with dismenorea
2) Confidence 0.21 Published 1997 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 9299442 Disease Relevance 0.17 Pain Relevance 0.14

General Comments

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