INT71314

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Context Info
Confidence 0.13
First Reported 1997
Last Reported 2008
Negated 1
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.84
Pain Relevance 1.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (Ptges3) cell proliferation (Ptges3) nucleus (Ptges3)
cytoplasm (Ptges3)
Ptges3 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 3 100.00 Very High Very High Very High
Glutamate 1 100.00 Very High Very High Very High
ketamine 2 98.92 Very High Very High Very High
tolerance 4 95.44 Very High Very High Very High
Morphine 7 94.92 High High
Physical dependence 4 93.76 High High
Abstinence syndrome 1 91.92 High High
opiate 2 90.84 High High
Glutamate receptor 1 75.00 Quite High
Inflammation 22 61.60 Quite High
Disease Link Frequency Relevance Heat
Drug Dependence 4 93.76 High High
Syndrome 1 91.48 High High
Myositis 27 90.16 High High
Polymyositis 10 85.28 High High
Dermatomyositis 11 83.92 Quite High
INFLAMMATION 24 61.60 Quite High
Opiate Addiction 1 27.36 Quite Low
Disease 6 5.00 Very Low Very Low Very Low
Muscle Weakness 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effects of the non-competitive antagonists of the glutamate complex receptor, dizocilpine (MK 801) and ketamine and of the competitive antagonist CGP 39551 were examined on the induction of tolerance to morphine, the development of physical dependence and the expression of the abstinence syndrome to the opiate in mice.
Spec (examined) Regulation (effects) of complex receptor associated with syndrome, morphine, glutamate, ketamine, physical dependence, antagonist, tolerance, opiate and abstinence syndrome
1) Confidence 0.13 Published 1997 Journal Eur. J. Pharmacol. Section Abstract Doc Link 9300257 Disease Relevance 0.26 Pain Relevance 0.93
Likewise, the distribution pattern or score for cPGES and COX-1 positive cells remained unchanged (fig 5A).
Neg (unchanged) Regulation (unchanged) of cPGES
2) Confidence 0.12 Published 2008 Journal Annals of the Rheumatic Diseases Section Body Doc Link PMC2582339 Disease Relevance 0.58 Pain Relevance 0.09

General Comments

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