INT71327

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Context Info
Confidence 0.60
First Reported 1997
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.51
Pain Relevance 1.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell death (Cacna1a) plasma membrane (Cacna1a) nucleus (Cacna1a)
neurological system process (Cacna1a) transmembrane transport (Cacna1a) cytoplasm (Cacna1a)
Cacna1a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Migraine 17 99.84 Very High Very High Very High
Calcium channel 4 89.52 High High
Neurotransmitter 1 87.08 High High
Disease Link Frequency Relevance Heat
Disease 2 100.00 Very High Very High Very High
Headache 3 99.84 Very High Very High Very High
Migraine With Aura 14 99.40 Very High Very High Very High
Spinocerebellar Ataxia Type 2 5 96.44 Very High Very High Very High
Ocular Toxicity (including Many Sub-types) 1 88.16 High High
Ataxia 5 87.28 High High
Epilepsy 1 77.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
[From gene to disease; from CACNA1A to migraine].
Localization (disease) of CACNA1A associated with migraine and disease
1) Confidence 0.60 Published 2001 Journal Ned Tijdschr Geneeskd Section Title Doc Link 11236374 Disease Relevance 0.83 Pain Relevance 0.90
Further studies with additional families will be necessary to reveal the importance of both CACNA1A and ATP1A2 genes on the pathogeneses of FHM in Brazil and to test the third gene (SCN1A) in these FHM families.
Localization (importance) of CACNA1A associated with migraine
2) Confidence 0.54 Published 2006 Journal Arq Neuropsiquiatr Section Abstract Doc Link 17119788 Disease Relevance 0.74 Pain Relevance 0.67
In the present work, the analysis of two new families with small CAG expansions of the CACNA1A gene is presented.
Localization (presented) of CACNA1A gene
3) Confidence 0.05 Published 1997 Journal Hum. Mol. Genet. Section Abstract Doc Link 9302278 Disease Relevance 0.94 Pain Relevance 0.13

General Comments

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