INT71350

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.01
First Reported 1997
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 3.92
Pain Relevance 4.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
nerve 1
dorsal root ganglion 1
interneurons 1
Tpnr1 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 23 100.00 Very High Very High Very High
gABA 8 100.00 Very High Very High Very High
referred pain 5 100.00 Very High Very High Very High
Demyelination 8 99.90 Very High Very High Very High
Thermal hyperalgesia 10 99.40 Very High Very High Very High
dorsal root ganglion 35 99.32 Very High Very High Very High
allodynia 14 98.90 Very High Very High Very High
Myofascial pain syndrome 4 98.68 Very High Very High Very High
Neuropathic pain 57 97.98 Very High Very High Very High
Sciatic nerve 13 97.48 Very High Very High Very High
Disease Link Frequency Relevance Heat
Pain 17 100.00 Very High Very High Very High
Referred Pain 5 100.00 Very High Very High Very High
Demyelinating Disease 8 99.90 Very High Very High Very High
Hyperalgesia 16 99.40 Very High Very High Very High
Neuropathic Pain 71 98.90 Very High Very High Very High
Ganglion Cysts 35 98.84 Very High Very High Very High
Myofascial Pain Syndromes 4 98.68 Very High Very High Very High
Nervous System Injury 64 94.84 High High
Nociception 29 89.56 High High
Low Back Pain 7 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Autotaxin, a synthetic enzyme of lysophosphatidic acid (LPA), mediates the induction of nerve-injured neuropathic pain

Recently, we reported that lysophosphatidic acid (LPA) induces long-lasting mechanical allodynia and thermal hyperalgesia as well as demyelination and upregulation of pain-related proteins through one of its cognate receptors, LPA1.

Positive_regulation (upregulation) of pain-related in nerve associated with pain, demyelination, allodynia, thermal hyperalgesia and neuropathic pain
1) Confidence 0.01 Published 2008 Journal Mol Pain Section Title Doc Link PMC2277392 Disease Relevance 1.62 Pain Relevance 1.02
Furthermore, LPC treatment of the saphenous or sciatic nerve induced neuropathic pain-like behaviors, such as mechanical allodynia and thermal hyperalgesia, as well as demyelination and upregulation of pain-related proteins in the dorsal root ganglion [20].
Positive_regulation (upregulation) of pain-related in dorsal root ganglion associated with ganglion cysts, dorsal root ganglion, pain, allodynia, neuropathic pain, demyelination, thermal hyperalgesia and sciatic nerve
2) Confidence 0.01 Published 2008 Journal Mol Pain Section Body Doc Link PMC2277392 Disease Relevance 1.07 Pain Relevance 0.76
In other words, pain-inhibitory GABA interneurons are maximally or submaximally activated by tonic nicotinic stimulation.
Positive_regulation (activated) of pain-inhibitory in interneurons associated with pain and gaba
3) Confidence 0.01 Published 2007 Journal Mol Pain Section Body Doc Link PMC2234393 Disease Relevance 0.48 Pain Relevance 1.36
Referred pain elicited by palpation and by needling of myofascial trigger points: a comparison.
Positive_regulation (elicited) of Referred pain associated with myofascial pain syndrome and referred pain
4) Confidence 0.00 Published 1997 Journal Arch Phys Med Rehabil Section Title Doc Link 9305268 Disease Relevance 0.76 Pain Relevance 0.94

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox