INT71378

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Context Info
Confidence 0.07
First Reported 1997
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.34
Pain Relevance 1.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear envelope (LBR) small molecule metabolic process (LBR) nucleus (LBR)
DNA binding (LBR)
Anatomy Link Frequency
PNS 1
T-lymphocyte 1
LBR (Homo sapiens)
Pain Link Frequency Relevance Heat
Neuritis 9 98.66 Very High Very High Very High
cytokine 4 98.40 Very High Very High Very High
Peripheral nervous system 3 93.62 High High
Demyelination 1 81.04 Quite High
Inflammation 1 80.32 Quite High
member 8 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Experimental Autoimmune Neuritis 9 98.66 Very High Very High Very High
Immunization 1 86.80 High High
Demyelinating Disease 1 81.04 Quite High
INFLAMMATION 1 80.32 Quite High
Syndrome 1 79.08 Quite High
Convalescence 1 75.00 Quite High
Hodgkin's Disease 77 69.68 Quite High
Disease 4 59.60 Quite High
Lymphatic System Cancer 25 54.16 Quite High
Anaplastic Large Cell Lymphoma 19 53.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The antibody recognised a single clone, RZPDp9028C1242, which was derived from a PHA-induced T-lymphocyte cDNA library.
Transcription (derived) of PHA-induced in T-lymphocyte
1) Confidence 0.07 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2829491 Disease Relevance 0.23 Pain Relevance 0
To study the involvement of immunoregulatory cytokines, we induced EAN in Lewis rats by immunizing with bovine PNS myelin (BPM) and Freund's complete adjuvant. mRNA expression of the cytokines IL-1beta, IL-6, IL-10, IL-12, TNF-alpha and TNF-beta, and the cytolytic effector molecule cytolysin was examined in lymph node mononuclear cells (MNC) over the course of EAN by in situ hybridization after culture without antigen and in the presence of BPM, the myelin P2 protein, the control antigen acetylcholine receptor, or the mitogen PHA.
Transcription (presence) of mitogen PHA in PNS associated with peripheral nervous system, neuritis and cytokine
2) Confidence 0.00 Published 1997 Journal J. Neuroimmunol. Section Abstract Doc Link 9307234 Disease Relevance 1.11 Pain Relevance 1.03

General Comments

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