INT7138

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Context Info
Confidence 0.36
First Reported 1984
Last Reported 2008
Negated 0
Speculated 1
Reported most in Abstract
Documents 10
Total Number 11
Disease Relevance 1.99
Pain Relevance 6.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Avp) extracellular space (Avp) extracellular region (Avp)
response to stress (Avp) signal transducer activity (Avp)
Anatomy Link Frequency
nucleus 4
neurons 2
pituitary 2
duct 2
posterior pituitary 2
Avp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
GABAergic 5 100.00 Very High Very High Very High
Acupuncture 4 100.00 Very High Very High Very High
fluoxetine 2 100.00 Very High Very High Very High
Catecholamine 2 100.00 Very High Very High Very High
Rostral ventrolateral medulla 1 100.00 Very High Very High Very High
narcan 28 99.80 Very High Very High Very High
antagonist 14 99.62 Very High Very High Very High
cocaine 14 99.60 Very High Very High Very High
Opioid 16 99.58 Very High Very High Very High
opioid receptor 4 99.40 Very High Very High Very High
Disease Link Frequency Relevance Heat
Hypoglycemia 6 99.20 Very High Very High Very High
Obesity 9 98.56 Very High Very High Very High
Paralysis 1 94.72 High High
Stress 5 89.44 High High
Pressure Volume 2 Under Development 2 77.52 Quite High
Chronic Renal Failure 124 76.64 Quite High
Drug Dependence 1 68.44 Quite High
Recurrence 1 67.88 Quite High
Hypertrophy 11 57.44 Quite High
Heart Rate Under Development 4 39.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The 5-HT precursor, 5-hydroxytryptophan, injected in combination with the 5-HT reuptake inhibitor, fluoxetine, increased oxytocin mRNA expression in the PVN, and the concentration of vasopressin and oxytocin in plasma, whereas mRNA in the SON was not affected.
Regulation (injected) of Regulation (concentration) of vasopressin in PVN associated with fluoxetine
1) Confidence 0.36 Published 2003 Journal J. Neuroendocrinol. Section Abstract Doc Link 12716407 Disease Relevance 0.09 Pain Relevance 0.45
[Effect of acupuncture on the contents of vasopressin and oxytocin in the rat].
Regulation ([Effect) of Regulation (contents) of vasopressin associated with acupuncture
2) Confidence 0.28 Published 1992 Journal Zhen Ci Yan Jiu Section Title Doc Link 1339632 Disease Relevance 0 Pain Relevance 0.31
The functional role of the nucleus tractus solitarius (NTS) in the regulation of arginine-vasopressin (AVP) release mediated by baroreceptor activation was investigated by examining the effects induced by the presynaptic alpha-adrenergic agonist clonidine.
Spec (investigated) Regulation (role) of Regulation (regulation) of AVP in nucleus associated with agonist and clonidine
3) Confidence 0.27 Published 1990 Journal Pharmacol. Biochem. Behav. Section Abstract Doc Link 1982697 Disease Relevance 0.08 Pain Relevance 0.30
Results indicate a somatostatinergic involvement in the regulation of the AVP response to physical exercise.
Regulation (involvement) of Regulation (regulation) of AVP
4) Confidence 0.27 Published 2008 Journal J Neural Transm Section Abstract Doc Link 18259681 Disease Relevance 0 Pain Relevance 0.73
These data suggest the involvement of a GABAergic mechanism in regulation of the AVP response to physical exercise in men.
Regulation (involvement) of Regulation (regulation) of AVP associated with gabaergic
5) Confidence 0.26 Published 1993 Journal Regul. Pept. Section Abstract Doc Link 8278634 Disease Relevance 0 Pain Relevance 0.91
Involvement of the septum in the regulation of paraventricular vasopressin neurons by the subfornical organ in the rat.
Regulation (Involvement) of Regulation (regulation) of vasopressin in neurons
6) Confidence 0.20 Published 1988 Journal Neurosci. Lett. Section Title Doc Link 3185990 Disease Relevance 0 Pain Relevance 0.16
These data indicate that an abnormal activity of endogenous opioids might account for the hypothalamic posterior pituitary dysfunction, which is responsible for the low AVP and OT responses to insulin-induced hypoglycemia in obesity.
Regulation (responsible) of Regulation (responses) of AVP in posterior pituitary associated with hypoglycemia, obesity and endogenous opioid
7) Confidence 0.16 Published 1990 Journal J. Endocrinol. Invest. Section Abstract Doc Link 2292659 Disease Relevance 1.04 Pain Relevance 0.38
The present studies were undertaken to determine whether: (1) 14-day (chronic) "binge" pattern cocaine administration (45 mg/kg/day) or its withdrawal for 3 h (acute), 1 day (subacute) or 10 days (chronic) alters arginine vasopressin mRNA levels in amygdala or hypothalamus; (2) the opioid receptor antagonist naloxone (1mg/kg) alters arginine vasopressin mRNA or hypothalamic-pituitary-adrenal hormonal responses in acute cocaine withdrawal; and (3) there are associated changes of mu opioid receptor or proopiomelanocortin mRNA levels.
Regulation (alters) of Regulation (responses) of vasopressin in pituitary associated with antagonist, mu opioid receptor, narcan, opioid receptor, amygdala, withdrawal and cocaine
8) Confidence 0.10 Published 2005 Journal Neuroscience Section Abstract Doc Link 16039786 Disease Relevance 0.36 Pain Relevance 1.23
Water permeability of the collecting duct is tightly regulated, under the control of the vasopressin, which causes a dramatic increase in collecting duct water permeability, allowing reabsorption of water from the tubular fluid down an osmotic gradient.
Regulation (regulated) of Regulation (control) of vasopressin in duct
9) Confidence 0.06 Published 2005 Journal Journal of Korean Medical Science Section Body Doc Link PMC2808601 Disease Relevance 0.25 Pain Relevance 0.03
Tonic vasomotor control by the rostral ventrolateral medulla: effect of electrical or chemical stimulation of the area containing C1 adrenaline neurons on arterial pressure, heart rate, and plasma catecholamines and vasopressin.
Regulation (control) of in medulla Regulation (effect) of vasopressin in plasma associated with rostral ventrolateral medulla and catecholamine
10) Confidence 0.03 Published 1984 Journal J. Neurosci. Section Title Doc Link 6699683 Disease Relevance 0.09 Pain Relevance 0.31
Opioids also seem to play a role in the regulation of vasopressin under some conditions of water balance.
Regulation (role) of Regulation (regulation) of vasopressin associated with opioid
11) Confidence 0.01 Published 1984 Journal Horm. Metab. Res. Section Abstract Doc Link 6088380 Disease Relevance 0.09 Pain Relevance 1.57

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