INT71408

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.27
First Reported 1997
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.21
Pain Relevance 0.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Nts)
Anatomy Link Frequency
RVM 2
Rvm (Mus musculus)
Nts (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Rostral ventromedial medulla 25 100.00 Very High Very High Very High
antagonist 3 86.84 High High
Glutamate 2 73.28 Quite High
nociceptor 2 25.00 Low Low
Dorsal horn neuron 1 25.00 Low Low
Pain 1 25.00 Low Low
wide dynamic range 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

8 100.00 Very High Very High Very High
Nociception 14 96.84 Very High Very High Very High
Paralysis 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Additionally, the facilitatory and inhibitory effects of neurotensin appear to occur via interaction with multiple neurotensin receptors in the RVM that activate independent systems that descend in the ventrolateral funiculi and DLFs, respectively.
RVM Binding (interaction) of neurotensin in RVM associated with rostral ventromedial medulla
1) Confidence 0.27 Published 1997 Journal J. Neurophysiol. Section Abstract Doc Link 9310442 Disease Relevance 0.44 Pain Relevance 0.52
The results obtained with SR48692 suggest that endogenous neurotensin in the RVM modulates VMR to noxious CRD via a prominent interaction with neurotensin receptors that mediate facilitatory influences and a lesser interaction with neurotensin receptors that mediate masked inhibitory influences.
RVM Binding (interaction) of neurotensin in RVM associated with rostral ventromedial medulla
2) Confidence 0.10 Published 1999 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 10381777 Disease Relevance 0.17 Pain Relevance 0.35

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox