INT71437

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Context Info
Confidence 0.27
First Reported 1997
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 5.63
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Atp11c) plasma membrane (Atp11c)
Anatomy Link Frequency
skin 2
Atp11c (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 1 89.48 High High
depression 2 79.28 Quite High
corticosteroid 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bullous Skin Disease 120 100.00 Very High Very High Very High
Blister 72 99.12 Very High Very High Very High
Skin Infection 10 93.12 High High
Burns 12 92.56 High High
Injury 8 92.16 High High
Death 1 90.48 High High
Disease 17 90.24 High High
Streptococcus Infection 2 88.96 High High
Acantholysis 4 88.76 High High
Adhesions 26 84.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
LPS-stimulated in vitro class-specific immunoglobulin (Ig) production was determined by enzyme-linked immunosorbent assay from splenic cell culture supernatants.
Positive_regulation (LPS-stimulated) of Spec (determined) Gene_expression (production) of Ig
1) Confidence 0.27 Published 1997 Journal J Burn Care Rehabil Section Abstract Doc Link 9313117 Disease Relevance 1.86 Pain Relevance 0.16
Furthermore, newborn mice treated with exfoliative toxins develop skin blisters similar to those observed with the passive transfer of PF Ig.
Positive_regulation (transfer) of Gene_expression (transfer) of Ig in skin associated with blister and bullous skin disease
2) Confidence 0.07 Published 2010 Journal Dermatology Research and Practice Section Body Doc Link PMC2902105 Disease Relevance 1.94 Pain Relevance 0
A similar expression profile was observed for Ig?
Positive_regulation (observed) of Gene_expression (observed) of Ig
3) Confidence 0.06 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1140086 Disease Relevance 0 Pain Relevance 0
Passive transfers of purified PF Ig into newborn mice produce blisters similar to those observed in PF patients [5, 6].
Positive_regulation (transfers) of Gene_expression (transfers) of Ig associated with blister and bullous skin disease
4) Confidence 0.05 Published 2010 Journal Dermatology Research and Practice Section Body Doc Link PMC2902105 Disease Relevance 1.84 Pain Relevance 0

General Comments

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