INT71476

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Context Info
Confidence 0.18
First Reported 1997
Last Reported 1997
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 1.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Creb1) mitochondrion (Creb1) nucleolus (Creb1)
nucleus (Creb1) DNA binding (Creb1) transcription factor binding (Creb1)
Creb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Locus ceruleus 11 99.70 Very High Very High Very High
Morphine 7 88.40 High High
opiate 6 75.60 Quite High
addiction 2 75.00 Quite High
withdrawal 2 71.36 Quite High
Physical dependence 1 33.28 Quite Low
Disease Link Frequency Relevance Heat
Toxicity 1 94.32 High High
Opiate Addiction 2 75.00 Quite High
Drug Dependence 1 33.28 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Infusion (5 d) of CREB antisense oligonucleotide directly into the LC significantly reduced levels of CREB immunoreactivity.
Negative_regulation (reduced) of Regulation (immunoreactivity) of CREB associated with locus ceruleus
1) Confidence 0.18 Published 1997 Journal J. Neurosci. Section Abstract Doc Link 9315909 Disease Relevance 0.17 Pain Relevance 1.06

General Comments

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