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Context Info
Confidence 0.00
First Reported 1997
Last Reported 1997
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il6) aging (Il6) extracellular region (Il6)
plasma membrane (OPRD1) cytoplasm (OPRD1) signal transducer activity (OPRD1)
Anatomy Link Frequency
immune system 3
OPRD1 (Homo sapiens)
Il6 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Opioid 1 98.20 Very High Very High Very High
antagonist 4 91.80 High High
opioid receptor 2 80.16 Quite High
Endogenous opioid 2 78.56 Quite High
cytokine 2 75.60 Quite High
Inflammation 1 75.24 Quite High
Disease Link Frequency Relevance Heat
Acute-phase Reaction 1 77.68 Quite High
INFLAMMATION 1 75.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The results show that mu-receptor blockade increases, whereas delta-receptor blockade decreases IL-6 induction, suggesting that the fine tuning exerted by opioids on the immune system may be achieved through a balance of opposing effects.
Negative_regulation (blockade) of delta-receptor in immune system Negative_regulation (decreases) of Positive_regulation (induction) of IL-6 in immune system associated with opioid
1) Confidence 0.00 Published 1997 Journal Am. J. Physiol. Section Abstract Doc Link 9321873 Disease Relevance 0.15 Pain Relevance 0.62

General Comments

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