INT71531

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.42
First Reported 1997
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 6
Disease Relevance 2.49
Pain Relevance 2.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Col4a4) cellular_component (Col4a4) biological_process (Col4a4)
Anatomy Link Frequency
PAG 1
nerves 1
brain 1
lymph 1
Col4a4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
qutenza 18 100.00 Very High Very High Very High
withdrawal 2 99.00 Very High Very High Very High
Arthritis 6 98.96 Very High Very High Very High
GABAergic 8 97.24 Very High Very High Very High
gABA 4 95.32 Very High Very High Very High
anesthesia 1 94.40 High High
Inflammatory response 1 86.88 High High
Periaqueductal grey 2 85.96 High High
cINOD 3 75.00 Quite High
Dismenorea 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 8 100.00 Very High Very High Very High
Anxiety Disorder 4 100.00 Very High Very High Very High
Urological Neuroanatomy 8 99.54 Very High Very High Very High
Experimental Arthritis 5 98.96 Very High Very High Very High
Fistula 4 89.12 High High
Aging 3 88.24 High High
INFLAMMATION 6 86.88 High High
Reprotox - General 1 2 75.00 Quite High
Arthritis 1 69.04 Quite High
Pressure And Volume Under Development 1 30.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the following day, lipid emulsion containing 35.4 mg/h of olive oil was infused intraduodenally for 7 h and lymph collected hourly was assayed for triglyceride and apolipoprotein A-IV (apo A-IV).
Positive_regulation (assayed) of A-IV in lymph associated with disorder of lipid metabolism
1) Confidence 0.42 Published 2000 Journal Mech. Ageing Dev. Section Abstract Doc Link 10714940 Disease Relevance 0.26 Pain Relevance 0.09
Stimulation of intestinal apolipoprotein A-IV by lipid is independent of capsaicin-sensitive afferent signals.
Positive_regulation (Stimulation) of A-IV associated with qutenza and disorder of lipid metabolism
2) Confidence 0.39 Published 1997 Journal Am. J. Physiol. Section Title Doc Link 9321877 Disease Relevance 0.34 Pain Relevance 0.70
These results do not support a role for capsaicin-sensitive, sensory afferent nerves in the stimulation of intestinal apo A-IV by dietary lipid.
Positive_regulation (stimulation) of A-IV in nerves associated with qutenza
3) Confidence 0.39 Published 1997 Journal Am. J. Physiol. Section Abstract Doc Link 9321877 Disease Relevance 0.29 Pain Relevance 0.63
In female rats, withdrawal from prolonged dosing with progesterone leads to upregulation of alpha4 and delta subunits of the GABAA receptor in several brain regions.
Positive_regulation (upregulation) of alpha4 in brain associated with withdrawal
4) Confidence 0.01 Published 2006 Journal Exp. Physiol. Section Abstract Doc Link 16740643 Disease Relevance 0.23 Pain Relevance 0.22
The effect of adjuvant arthritis (AA) on the pattern of rat serum proteins includes the upregulation of haptoglobin, orosomucoid, alpha2-macroglobulin, serine protease inhibitor-3, thiostatin, alpha1-antitrypsin, C-reactive protein, and the downregulation of kallikrein-binding protein, alpha1-inhibitor III, apolipoprotein A-I, alpha2-HS-glycoprotein, albumin, apolipoprotein A-IV, transthyretin and transferrin.
Positive_regulation (upregulation) of A-IV associated with experimental arthritis, disorder of lipid metabolism and arthritis
5) Confidence 0.01 Published 2000 Journal Electrophoresis Section Abstract Doc Link 10892728 Disease Relevance 0.92 Pain Relevance 0.45
In the PAG, a region involved in mediating panic-like anxiety, alpha4, beta1 and delta GABAA receptor subunits are located principally on GABAergic interneurones.
Positive_regulation (mediating) of alpha4 in PAG associated with gabaergic, anxiety disorder and urological neuroanatomy
6) Confidence 0.01 Published 2006 Journal Exp. Physiol. Section Abstract Doc Link 16740643 Disease Relevance 0.45 Pain Relevance 0.41

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox