INT71601

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Context Info
Confidence 0.60
First Reported 1997
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 11
Total Number 12
Disease Relevance 6.55
Pain Relevance 0.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (ACD) chromosome (ACD) nucleus (ACD)
intracellular (ACD) DNA binding (ACD)
Anatomy Link Frequency
plaque 1
skin 1
ankle 1
ACD (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 54 100.00 Very High Very High Very High
cINOD 4 99.86 Very High Very High Very High
nud 2 78.16 Quite High
cytokine 18 77.52 Quite High
psoriasis 44 74.92 Quite High
headache 1 64.16 Quite High
methotrexate 2 60.20 Quite High
tolerance 1 56.48 Quite High
Restless leg syndrome 8 50.00 Quite Low
alcohol 8 48.56 Quite Low
Disease Link Frequency Relevance Heat
Dermatitis 80 100.00 Very High Very High Very High
INFLAMMATION 60 100.00 Very High Very High Very High
Coronary Heart Disease 16 100.00 Very High Very High Very High
Skin Diseases 6 100.00 Very High Very High Very High
Atherosclerosis 5 98.72 Very High Very High Very High
Rupture 2 98.34 Very High Very High Very High
Hypersensitivity 14 94.92 High High
Disease 44 92.00 High High
Psoriasis 80 91.48 High High
Increased Venous Pressure Under Development 16 91.24 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Topical ketoprofen (KP), a nonsteroidal anti-inflammatory drug (NSAID), can induce ACD and photo-ACD.
Positive_regulation (induce) of ACD associated with inflammation, cinod and dermatitis
1) Confidence 0.60 Published 2008 Journal Curr. Pharm. Des. Section Abstract Doc Link 18991702 Disease Relevance 1.23 Pain Relevance 0.20
Topical ketoprofen (KP), a nonsteroidal anti-inflammatory drug (NSAID), can induce ACD and photo-ACD.
Positive_regulation (induce) of ACD associated with inflammation, cinod and dermatitis
2) Confidence 0.60 Published 2008 Journal Curr. Pharm. Des. Section Abstract Doc Link 18991702 Disease Relevance 1.23 Pain Relevance 0.20
Group ACD I
Positive_regulation (Group) of ACD
3) Confidence 0.43 Published 2010 Journal Korean Journal of Ophthalmology : KJO Section Body Doc Link PMC2817817 Disease Relevance 0 Pain Relevance 0
At the end of treatment, the absolute increase of ACD was significantly greater in sulodexide-treated patients (p < 0.01) with respect to the pentoxifylline-treated group.
Positive_regulation (increase) of ACD
4) Confidence 0.40 Published 1997 Journal Curr Med Res Opin Section Abstract Doc Link 9327192 Disease Relevance 0.93 Pain Relevance 0.16
Patients also were characterized on ankle-brachial index (ABI), ischemic window (IW) after a treadmill test, as well as initial claudication distance (ICD), and absolute claudication distance (ACD) during treadmill exercise.
Positive_regulation (characterized) of ACD in ankle
5) Confidence 0.37 Published 2008 Journal J. Vasc. Surg. Section Body Doc Link 18771878 Disease Relevance 0.08 Pain Relevance 0
Patients were categorized into quartiles based on the increase in ACD, which were subsequently related to change in WIQ and quality of life.
Positive_regulation (increase) of ACD
6) Confidence 0.36 Published 2009 Journal J. Vasc. Surg. Section Body Doc Link 19563956 Disease Relevance 0.08 Pain Relevance 0
Analysis of the four quartiles compared to an increase in ACD showed that a greater increase in ACD corresponded with a greater increase in WIQ score, from 0.06 to 0.25 (P = .011).
Positive_regulation (increase) of ACD
7) Confidence 0.36 Published 2009 Journal J. Vasc. Surg. Section Body Doc Link 19563956 Disease Relevance 0.06 Pain Relevance 0
Analysis of the four quartiles compared to an increase in ACD showed that a greater increase in ACD corresponded with a greater increase in WIQ score, from 0.06 to 0.25 (P = .011).
Positive_regulation (increase) of ACD
8) Confidence 0.36 Published 2009 Journal J. Vasc. Surg. Section Body Doc Link 19563956 Disease Relevance 0.06 Pain Relevance 0
In contrast, induction of ACD to polyaromatic hydrocarbons requires the biosynthesis of a reactive oxidative intermediate by cytochrome P450-dependent enzymes [58].
Positive_regulation (induction) of ACD associated with dermatitis
9) Confidence 0.24 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2929514 Disease Relevance 0.68 Pain Relevance 0.08
Allergic contact dermatitis (ACD) is a common inflammatory skin disease, induced by repeated contact with low molecular weight, highly reactive chemicals called haptens [48].
Positive_regulation (induced) of ACD in skin associated with inflammation, skin diseases and dermatitis
10) Confidence 0.17 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2929514 Disease Relevance 1.49 Pain Relevance 0.26
Distinct from plaque rupture in atherosclerotic native coronaries, progressive NI accumulation is the ultimate cause of ACD as well as allograft ISR[1].
Positive_regulation (cause) of ACD in plaque associated with atherosclerosis, rupture and coronary heart disease
11) Confidence 0.13 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2267220 Disease Relevance 0.48 Pain Relevance 0
The peripheral ACD could be more related to IOP elevation than central ACD.



Positive_regulation (elevation) of ACD
12) Confidence 0.04 Published 2008 Journal The Open Ophthalmology Journal Section Abstract Doc Link PMC2687102 Disease Relevance 0.24 Pain Relevance 0

General Comments

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