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Context Info
Confidence 0.34
First Reported 1992
Last Reported 1992
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.86

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peptidase activity (Ctsb) mitochondrion (Ctsb) extracellular space (Ctsb)
extracellular region (Ctsb) response to stress (Ctsb) lysosome (Ctsb)
Ctsb (Rattus norvegicus)
Pain Link Frequency Relevance Heat
bradykinin 23 100.00 Very High Very High Very High
Enkephalin 6 75.00 Quite High
antagonist 2 63.32 Quite High


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cathepsin B activation by BK or L-Arg but not des-Arg9-BK was inhibited by L-NMMA (inhibitor of NO synthesis), and the activation by L-Arg was enhanced by beta-glycerophosphate (beta-GP: inhibitor of phosphatases), while the activation by BK or des-Arg9-BK was inhibited by beta-GP.
Negative_regulation (inhibited) of Positive_regulation (activation) of Cathepsin B associated with bradykinin
1) Confidence 0.34 Published 1992 Journal J Osaka Univ Dent Sch Section Abstract Doc Link 1341708 Disease Relevance 0 Pain Relevance 0.86

General Comments

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