INT71760

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Context Info
Confidence 0.48
First Reported 1997
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 9
Total Number 12
Disease Relevance 2.84
Pain Relevance 5.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
spinal component 1
body 1
CSE (Homo sapiens)
Pain Link Frequency Relevance Heat
epidural 643 100.00 Very High Very High Very High
analgesia 480 100.00 Very High Very High Very High
Opioid 109 99.76 Very High Very High Very High
intrathecal 100 99.60 Very High Very High Very High
headache 40 98.88 Very High Very High Very High
local anesthetic 141 98.34 Very High Very High Very High
Pain 115 97.44 Very High Very High Very High
Inflammation 13 96.00 Very High Very High Very High
anesthesia 32 92.64 High High
nud 22 91.48 High High
Disease Link Frequency Relevance Heat
Viral Meningitis 4 99.98 Very High Very High Very High
Meningitis 16 98.92 Very High Very High Very High
Headache 8 98.88 Very High Very High Very High
Neck Pain 4 97.84 Very High Very High Very High
Pain 112 96.36 Very High Very High Very High
INFLAMMATION 10 96.00 Very High Very High Very High
Bacteremia 4 94.12 High High
Foreign Bodies 4 93.56 High High
Syndrome 5 92.68 High High
Dyspepsia 22 91.48 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CSE has also been associated with more rapid cervical dilation when compared to epidural analgesia in nulliparous women in early labor.
CSE Binding (associated) of associated with epidural and analgesia
1) Confidence 0.48 Published 2002 Journal Semin. Perinatol. Section Abstract Doc Link 12005469 Disease Relevance 0 Pain Relevance 0.98
A recent government commissioned by the Department of Women and Child Development (India) estimated the number of persons trafficked for CSE in India to be around 2.8 million, an increase of 22% from an earlier estimate [5,6].
CSE Binding (trafficked) of
2) Confidence 0.32 Published 2008 Journal Int J Equity Health Section Body Doc Link PMC2569945 Disease Relevance 0.21 Pain Relevance 0
The biggest supply states include: Andhra Pradesh (16/23 districts affected by trafficking for CSE), Bihar (24/38 districts affected by trafficking), Madhya Pradesh, West Bengal, Karnataka (16/27 districts affected by CSE), Tamil Nadu, Maharashtra, and Uttar Pradesh.
CSE Binding (trafficking) of
3) Confidence 0.32 Published 2008 Journal Int J Equity Health Section Body Doc Link PMC2569945 Disease Relevance 0 Pain Relevance 0
The United Nations (UN) estimates that the trafficking of women and children for CSE in Asia has victimized over 30 million people [3].
CSE Binding (victimized) of
4) Confidence 0.32 Published 2008 Journal Int J Equity Health Section Body Doc Link PMC2569945 Disease Relevance 0 Pain Relevance 0
Along with the use of low-dose mixtures of local anesthetics and opioids, and the introduction of fine-gauge pencil-point needles, CSE is being increasingly recognized as another important addition to the armamentarium of the anesthesiologist.
CSE Binding (recognized) of associated with epidural, opioid and local anesthetic
5) Confidence 0.31 Published 1997 Journal Reg Anesth Section Abstract Doc Link 9338901 Disease Relevance 0 Pain Relevance 0.37
However, case reports of meningitis following CSE appeared in the journals beginning mid 1990s.30–32 There was also a case of aseptic meningitis associated with the spinal component of the CSE technique.33
CSE Binding (associated) of in spinal component associated with meningitis, epidural and viral meningitis
6) Confidence 0.29 Published 2010 Journal International Journal of Women's Health Section Body Doc Link PMC2971703 Disease Relevance 1.06 Pain Relevance 0.97
Later, Miro et al also confirmed the safety of CSE, with similar findings, in a retrospective study involving 6497 cases.59


CSE Binding (safety) of associated with epidural
7) Confidence 0.29 Published 2010 Journal International Journal of Women's Health Section Body Doc Link PMC2971703 Disease Relevance 0.15 Pain Relevance 0.99
g of sufentanil).38 When lower doses of intrathecal opioids were used, CSE analgesia was shown not to be associated with adverse outcome for the fetus.
CSE Binding (associated) of associated with epidural, opioid, analgesia and intrathecal
8) Confidence 0.29 Published 2010 Journal International Journal of Women's Health Section Body Doc Link PMC2971703 Disease Relevance 0.36 Pain Relevance 0.92
Theoretically, CSE could be associated with an increased risk of meningitis compared with epidural alone because the dura (protective barrier for CNS) is punctured deliberately during CSE and then a foreign body (an epidural catheter), is placed nearby.
CSE Binding (associated) of in body associated with meningitis, epidural and foreign bodies
9) Confidence 0.28 Published 2010 Journal International Journal of Women's Health Section Body Doc Link PMC2971703 Disease Relevance 0.47 Pain Relevance 0.76
CSE had a faster onset of effective analgesia from time of injection but was associated with more pruritus.
CSE Binding (associated) of
10) Confidence 0.17 Published 2007 Journal Cochrane Database Syst Rev Section Body Doc Link 17636721 Disease Relevance 0 Pain Relevance 0
CSE was also associated with a clinically non-significant lower umbilical arterial pH.
CSE Binding (associated) of
11) Confidence 0.17 Published 2007 Journal Cochrane Database Syst Rev Section Body Doc Link 17636721 Disease Relevance 0 Pain Relevance 0
-lyase (CSE) [1-5], is increasingly recognized as a biologically important signaling molecule in various tissues and processes including pain and inflammation [6,7].
CSE Binding (recognized) of associated with pain and inflammation
12) Confidence 0.02 Published 2009 Journal Mol Pain Section Body Doc Link PMC2731739 Disease Relevance 0.59 Pain Relevance 0.42

General Comments

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