INT71888

Context Info Confidence 0.00 First Reported 1997 Last Reported 1997 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.39 Pain Relevance 0.29

cytosol (Nfkb1, Nfkb1) signal transduction (Nfkb1, Nfkb1) mitochondrion (Nfkb1, Nfkb1) nucleus (Nfkb1, Nfkb1) DNA binding (Nfkb1, Nfkb1) nucleic acid binding transcription factor activity (Nfkb1, Nfkb1)

Nfkb1 (Mus musculus) Nfkb1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Potency 1 97.08 Inflammation 5 96.76 cINOD 2 50.56

Disease Link Frequency Relevance Heat INFLAMMATION 6 96.76

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

NF-kappaB, which resides in an inactive, cytoplasmic complex in unstimulated cells, is activated by phosphorylation and degradation of its inhibitory subunit, IkappaB.

Phosphorylation (phosphorylation) of IkappaB Positive_regulation (activated) of NF-kappaB

1) Confidence 0.00 Published 1997 Journal Biol. Chem. Section Abstract Doc Link 9348104 Disease Relevance 0.39 Pain Relevance 0.29

General Comments

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