INT71987

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Context Info
Confidence 0.60
First Reported 1997
Last Reported 1997
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Sptan1) plasma membrane (Sptan1) cytoskeleton (Sptan1)
protein complex (Sptan1) cytoplasm (Sptan1)
Anatomy Link Frequency
neurons 2
Sptan1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 6 98.82 Very High Very High Very High
adenocard 4 93.44 High High
agonist 2 92.24 High High
Opioid 1 86.92 High High
antagonist 3 86.32 High High
Nucleus accumbens 2 76.32 Quite High
opioid receptor 3 75.00 Quite High
Dopamine 2 69.60 Quite High
mu opioid receptor 1 59.08 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus chronic D1 blockade, like chronic morphine treatment, appears to cause a selective impairment of the regulation of adenylyl cyclase in A2a receptor-expressing striato-pallidal neurons.
Regulation (regulation) of Gene_expression (expressing) of A2a in neurons associated with morphine
1) Confidence 0.60 Published 1997 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 9353370 Disease Relevance 0 Pain Relevance 1.03

General Comments

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