INT72022

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Context Info
Confidence 0.32
First Reported 1997
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.07
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Ednra) plasma membrane (Ednra) signal transducer activity (Ednra)
Ednra (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 2 100.00 Very High Very High Very High
tetrodotoxin 2 86.04 High High
agonist 1 67.96 Quite High
Disease Link Frequency Relevance Heat
Hypoxia 1 65.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Antagonism of hypothalamic ET(A) receptors potentiated the stimulatory effect of ET-1 and ET-3 on neurohypophysial secretion, an effect not observed with ET(B) receptor-induced somatodendritic release of AVP.
Positive_regulation (induced) of Localization (release) of ET
1) Confidence 0.32 Published 2004 Journal Am. J. Physiol. Endocrinol. Metab. Section Abstract Doc Link 14665445 Disease Relevance 0 Pain Relevance 0.12
Our method of real-time monitoring of dopamine release from rat striatal slices revealed that endothelin (ET)-3-induced dopamine release was inhibited by NG-methyl-L-arginine (L-NMMA; 1 mM), an inhibitor of nitric oxide (NO) synthase, while NG-methyl-D-arginine (D-NMMA; 1 mM), an inactive isomer of L-NMMA, had no effect. 2.
Positive_regulation (-3-induced) of Localization (release) of ET associated with dopamine
2) Confidence 0.28 Published 1997 Journal Cell. Mol. Neurobiol. Section Abstract Doc Link 9353589 Disease Relevance 0.07 Pain Relevance 0.18

General Comments

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