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Context Info
Confidence 0.45
First Reported 1997
Last Reported 1997
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tnf) extracellular space (Tnf) extracellular region (Tnf)
plasma membrane (Tnf) intracellular (Tnf) extracellular matrix organization (Tnf)
Anatomy Link Frequency
nerve 2
Tnf (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 1 96.64 Very High Very High Very High
Central nervous system 3 82.16 Quite High
Clonidine 1 77.88 Quite High
agonist 1 77.48 Quite High
antidepressant 1 75.00 Quite High
tricyclic antidepressant 1 63.92 Quite High
Desipramine 1 61.92 Quite High
Hippocampus 1 57.84 Quite High
Locus ceruleus 1 56.56 Quite High
cytokine 1 37.68 Quite Low
Disease Link Frequency Relevance Heat
Necrosis 2 75.08 Quite High
Cancer 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Presently, we demonstrate that similar to alpha 2-adrenergic activation, TNF alpha regulation of NE release in a region of the brain rich in noradrenergic nerve terminals, is dependent upon the frequency of electrical stimulation applied to the hippocampal slice.
Regulation (dependent) of Regulation (regulation) of TNF alpha in nerve
1) Confidence 0.45 Published 1997 Journal J. Neuroimmunol. Section Abstract Doc Link 9357451 Disease Relevance 0.30 Pain Relevance 0.40

General Comments

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