INT72151

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Context Info
Confidence 0.01
First Reported 1997
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.49
Pain Relevance 0.88

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (MYOT)
MYOT (Homo sapiens)
Pain Link Frequency Relevance Heat
MU agonist 2 98.96 Very High Very High Very High
Enkephalin 1 98.54 Very High Very High Very High
Opioid 2 87.20 High High
opioid receptor 3 85.20 High High
induced neuropathy 1 83.88 Quite High
Neurotransmitter 1 83.04 Quite High
Pain 1 81.20 Quite High
Kinase C 1 80.92 Quite High
tolerance 1 66.04 Quite High
Central nervous system 2 63.68 Quite High
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 1 99.60 Very High Very High Very High
Drug Induced Neurotoxicity 6 98.72 Very High Very High Very High
Adhesions 3 93.84 High High
Neuropathic Pain 3 83.88 Quite High
Pain 1 81.20 Quite High
Hypesthesia 1 80.84 Quite High
Dysesthesia 1 80.44 Quite High
Toxicity 7 78.08 Quite High
Neurological Disease 3 75.48 Quite High
Hepatotoxicity 8 73.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, arsenic-induced neurotoxicity, like many other neurodegenerative diseases, causes changes in cytoskeletal protein composition and hyperphosphorylation.
Phosphorylation (hyperphosphorylation) of cytoskeletal protein associated with drug induced neurotoxicity and neurodegenerative disease
1) Confidence 0.01 Published 2010 Journal Environ Health Section Body Doc Link PMC2911418 Disease Relevance 1.24 Pain Relevance 0.24
We also demonstrate that met-enkephalin, a mu-opioid agonist in E6CH cultures, significantly increases tyrosine phosphorylation of another Src kinase substrate, the cytoskeletal protein cortactin.
Phosphorylation (phosphorylation) of cytoskeletal protein associated with mu agonist and enkephalin
2) Confidence 0.00 Published 1997 Journal J. Neurosci. Res. Section Abstract Doc Link 9364324 Disease Relevance 0.25 Pain Relevance 0.64

General Comments

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