INT72295

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Context Info
Confidence 0.39
First Reported 1997
Last Reported 1997
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.10
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lyase activity (CA3) cytoplasm (CA3)
Anatomy Link Frequency
cortex 2
CA3 (Homo sapiens)
Pain Link Frequency Relevance Heat
lidocaine 1 99.20 Very High Very High Very High
tetrodotoxin 1 98.94 Very High Very High Very High
sodium channel 1 98.36 Very High Very High Very High
Action potential 3 96.88 Very High Very High Very High
Disease Link Frequency Relevance Heat
Death 1 97.56 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although respective blockade of inhibitory and excitatory neurotransmission by picrotoxin and CNQX did not significantly induce cell death in all hippocampal area, sodium channel blocking drugs (tetrodotoxin or lidocaine) caused specific and severe damage and affected the formation of functional synapse in CA1 and the entorhinal cortex but not in CA3.
Neg (not) Regulation (affected) of CA3 Binding (formation) of in cortex associated with tetrodotoxin, sodium channel, lidocaine and death
1) Confidence 0.39 Published 1997 Journal Brain Res. Dev. Brain Res. Section Abstract Doc Link 9370066 Disease Relevance 0.10 Pain Relevance 0.38

General Comments

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