INT72311

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Context Info
Confidence 0.00
First Reported 1996
Last Reported 1996
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.33
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Vcam1) aging (Vcam1) cell adhesion (Vcam1)
Anatomy Link Frequency
reticulocytes 1
reticulocyte alpha 4 beta 1 (Mus musculus)
Vcam1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 1 98.16 Very High Very High Very High
Pain 1 77.04 Quite High
Disease Link Frequency Relevance Heat
Adhesions 1 100.00 Very High Very High Very High
Pain 1 77.04 Quite High
Sickle Cell Anemia 3 76.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Four receptor-mediated adherence pathways have been described to date: adherence mediated by high molecular weight von Willebrand factor multimers bridging glycoprotein lb-like and integrin receptors on sickle cells and similar receptors on endothelial cells; thrombospondin bridging CD36 on sickle reticulocytes and the alpha v beta 3 integrin on large-vessel endothelial cells or alpha v beta 3 and CD36 on microvascular endothelium; binding of sickle reticulocyte alpha 4 beta 1 receptors to vascular cell adhesion molecule 1 expressed on endothelial cells stimulated by cytokine or double-stranded RNA viruses; and binding of sickle cells to endothelial cell-associated fibronectin via sickle reticulocyte alpha 4 beta 1 activated by phorbol ester or interleukin-8.
reticulocyte alpha 4 beta 1 Binding (binding) of vascular cell adhesion molecule 1 in reticulocytes associated with adhesions and cytokine
1) Confidence 0.00 Published 1996 Journal Curr. Opin. Hematol. Section Abstract Doc Link 9372061 Disease Relevance 0.33 Pain Relevance 0.13

General Comments

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