INT72322

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.49
First Reported 1997
Last Reported 2002
Negated 1
Speculated 0
Reported most in Title
Documents 5
Total Number 6
Disease Relevance 0
Pain Relevance 3.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Htr1a) signal transducer activity (Htr1a)
Htr1a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
fluoxetine 30 100.00 Very High Very High Very High
Serotonin 6 97.08 Very High Very High Very High
noradrenaline 2 96.40 Very High Very High Very High
Raphe 10 96.08 Very High Very High Very High
sNRI 2 95.04 Very High Very High Very High
Potency 12 82.88 Quite High
antagonist 2 81.80 Quite High
agonist 4 80.40 Quite High
tricyclic antidepressant 2 65.88 Quite High
sSRI 2 55.80 Quite High

|}

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study, we investigated whether a link might exist between these effects, i.e., whether glucocorticoid receptor activation could be responsible for the fluoxetine-induced desensitization of 5-HT1A autoreceptors.
Positive_regulation (fluoxetine-induced) of Localization (desensitization) of 5-HT1A associated with fluoxetine
1) Confidence 0.49 Published 1997 Journal Synapse Section Abstract Doc Link 9372553 Disease Relevance 0 Pain Relevance 0.60
In the present study, we investigated whether a link might exist between these effects, i.e., whether glucocorticoid receptor activation could be responsible for the fluoxetine-induced desensitization of 5-HT1A autoreceptors.
Positive_regulation (activation) of Localization (desensitization) of 5-HT1A associated with fluoxetine
2) Confidence 0.49 Published 1997 Journal Synapse Section Abstract Doc Link 9372553 Disease Relevance 0 Pain Relevance 0.60
Fluoxetine-induced desensitization of somatodendritic 5-HT1A autoreceptors is independent of glucocorticoid(s).
Positive_regulation (Fluoxetine-induced) of Localization (desensitization) of 5-HT1A associated with fluoxetine
3) Confidence 0.49 Published 1997 Journal Synapse Section Title Doc Link 9372553 Disease Relevance 0 Pain Relevance 0.53
Fluoxetine-induced desensitization of somatodendritic 5-HT1A autoreceptors is independent of glucocorticoid(s).
Neg (independent) Positive_regulation (independent) of Localization (desensitization) of 5-HT1A associated with fluoxetine
4) Confidence 0.49 Published 1997 Journal Synapse Section Title Doc Link 9372553 Disease Relevance 0 Pain Relevance 0.54
Repeated administration of milnacipran induces rapid desensitization of somatodendritic 5-HT1A autoreceptors but not postsynaptic 5-HT1A receptors.
Positive_regulation (induces) of Localization (desensitization) of 5-HT1A
5) Confidence 0.49 Published 2002 Journal J. Psychopharmacol. (Oxford) Section Title Doc Link 12236634 Disease Relevance 0 Pain Relevance 0.41
Repeated administration of milnacipran induces rapid desensitization of somatodendritic 5-HT1A autoreceptors but not postsynaptic 5-HT1A receptors.
Positive_regulation (induces) of Localization (desensitization) of 5-HT1A
6) Confidence 0.49 Published 2002 Journal J. Psychopharmacol. (Oxford) Section Title Doc Link 12236634 Disease Relevance 0 Pain Relevance 0.40

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox