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Context Info
Confidence 0.32
First Reported 1997
Last Reported 1997
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.09
Pain Relevance 0.54

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cytoplasm (Trim13, Shc1) mitochondrion (Shc1) aging (Shc1)
endoplasmic reticulum (Trim13) intracellular (Trim13) ligase activity (Trim13)
Trim13 (Mus musculus)
Shc1 (Mus musculus)
Pain Link Frequency Relevance Heat
Enkephalin 4 100.00 Very High Very High Very High
opioid receptor 2 78.40 Quite High
agonist 1 75.00 Quite High
MU agonist 1 69.72 Quite High
Disease Link Frequency Relevance Heat
Bordatella Infection 1 93.12 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Half-maximal effects of D-ala2-D-leu5-enkephalin on p52 Shc tyrosine phosphorylation were produced with sub-nanomolar concentrations, in agreement with previous results on the tyrosine phosphorylation of p44MAPK (Burt et al., 1996). p52 Shc became tyrosine phosphorylated more rapidly than p44MAPK in response to D-ala2-D-leu5-enkephalin and its enhanced tyrosine phosphorylation was maintained for at least 10 min.
leu5 Regulation (effects) of Phosphorylation (phosphorylation) of p52 Shc associated with enkephalin
1) Confidence 0.32 Published 1997 Journal Cell. Signal. Section Abstract Doc Link 9376223 Disease Relevance 0.09 Pain Relevance 0.54

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