INT7247

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Context Info
Confidence 0.08
First Reported 1992
Last Reported 1994
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 0.22

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signal transduction (GNRH1) extracellular space (GNRH1) extracellular region (GNRH1)
cell-cell signaling (GNRH1)
GNRH1 (Homo sapiens)
Lhb (Mus musculus)
Pain Link Frequency Relevance Heat
Endogenous opioid 1 98.40 Very High Very High Very High
Central nervous system 1 75.00 Quite High
agonist 2 60.00 Quite High
excitatory amino acid 1 58.80 Quite High
Glutamate 1 55.28 Quite High
Opioid 3 50.00 Quite Low
Morphine 1 46.72 Quite Low
antagonist 1 44.48 Quite Low
narcan 5 43.52 Quite Low
Disease Link Frequency Relevance Heat
Polycystic Ovary Syndrome 3 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Reduced LH pulse amplitude, induced by naltrexone, was not associated with a reduced LH response to GnRH or with a reduction in mean LH levels.
GnRH Binding (associated) of LH
1) Confidence 0.08 Published 1994 Journal Fertil. Steril. Section Body Doc Link 8034071 Disease Relevance 0 Pain Relevance 0
We recently demonstrated that pulsatile LH secretion is associated with pulsatile gonadotropin releasing hormone (GnRH) in the pig.
gonadotropin releasing hormone Binding (associated) of LH
2) Confidence 0.01 Published 1992 Journal J. Physiol. Pharmacol. Section Abstract Doc Link 1343978 Disease Relevance 0 Pain Relevance 0.22

General Comments

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