INT72583

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Context Info
Confidence 0.00
First Reported 1997
Last Reported 1997
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.56
Pain Relevance 0.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Htr1a) plasma membrane (Htr1a) signal transducer activity (Htr1a)
Htr1a (Mus musculus)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 14 99.28 Very High Very High Very High
agonist 6 76.24 Quite High
Sumatriptan 4 75.20 Quite High
Disease Link Frequency Relevance Heat
Repression 4 88.56 High High
Cluster Headache 4 59.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results demonstrate that activation of the endogenous 5-HT1 receptor is coupled to calcium signaling pathways and leads to inhibition of CGRP gene transcription.
Positive_regulation (coupled) of Positive_regulation (activation) of 5-HT1 receptor associated with calcitonin gene-related peptide
1) Confidence 0.00 Published 1997 Journal J. Neurosci. Section Abstract Doc Link 9391009 Disease Relevance 0.28 Pain Relevance 0.49
These results demonstrate that activation of the endogenous 5-HT1 receptor is coupled to calcium signaling pathways and leads to inhibition of CGRP gene transcription.
Positive_regulation (leads) of Positive_regulation (activation) of 5-HT1 receptor associated with calcitonin gene-related peptide
2) Confidence 0.00 Published 1997 Journal J. Neurosci. Section Abstract Doc Link 9391009 Disease Relevance 0.28 Pain Relevance 0.49

General Comments

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