INT72601

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Context Info
Confidence 0.32
First Reported 1997
Last Reported 2010
Negated 2
Speculated 1
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 0.51
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (ITGA5) plasma membrane (ITGA5)
Anatomy Link Frequency
stem cells 1
ITGA5 (Homo sapiens)
Pain Link Frequency Relevance Heat
tetrodotoxin 12 59.80 Quite High
endometriosis 4 50.00 Quite Low
Dismenorea 4 50.00 Quite Low
gABA 2 19.24 Low Low
Dopamine 3 18.80 Low Low
agonist 2 15.96 Low Low
Glutamate 2 15.28 Low Low
addiction 2 13.68 Low Low
ischemia 12 5.00 Very Low Very Low Very Low
Inflammation 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 19 99.24 Very High Very High Very High
Dysmenorrhea 4 86.60 High High
Endometriosis (extended) 4 86.00 High High
Adhesions 3 50.00 Quite Low
Brain Hemorrhage 39 5.00 Very Low Very Low Very Low
Disease 15 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 13 5.00 Very Low Very Low Very Low
INFLAMMATION 10 5.00 Very Low Very Low Very Low
Brain Injury 9 5.00 Very Low Very Low Very Low
Injury 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Adipose tissue-derived stem cells are understood to express surface markers of CD9, CD10, CD13, CD29, CD44, CD49d, CD49e, CD54, CD55, CD59, CD73, CD90, CD105, CD146, CD166, and STRO-1, and lack hematopoietic lineage markers CD11b, CD14, CD19, CD34, and CD45 [20,34,50-53].
Neg (lack) Gene_expression (express) of CD49e in stem cells associated with obesity
1) Confidence 0.32 Published 2010 Journal BMC Cell Biol Section Body Doc Link PMC2867791 Disease Relevance 0.17 Pain Relevance 0.06
The microarray gene expression analysis of these cells indicates that the cells are negative for the hematopoietic markers CD34, CD49c, CD49d, CD62e, CD62p, CD106, CD117, CD133, CD235a, HLA-DRB4, HLA-DRB4 and HAS1, and positive for the mesenchymal markers CD13, CD29, CD44, CD49a/b, CD49e, CD73, CD105 and vimentin [18], supporting their USSCs/MSC origin.
Neg (negative) Gene_expression (negative) of CD49e
2) Confidence 0.24 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2956109 Disease Relevance 0 Pain Relevance 0
The samples were immunohistochemically examined for the expression of very late activation antigen-2 (VLA-2), VLA-3, VLA-4, VLA-5, VLA-6, and E-cadherin.
Spec (examined) Gene_expression (expression) of VLA-5
3) Confidence 0.05 Published 1997 Journal J. Obstet. Gynaecol. Res. Section Body Doc Link 9392916 Disease Relevance 0.17 Pain Relevance 0
RESULTS: The expression of each VLA molecule and E-cadherin except VLA-4, VLA-5, and VLA-6 was significantly increased throughout the menstrual cycle in endometria in both the endometriosis and adenomyosis groups.
Gene_expression (expression) of VLA-5
4) Confidence 0.04 Published 1997 Journal J. Obstet. Gynaecol. Res. Section Body Doc Link 9392916 Disease Relevance 0.16 Pain Relevance 0

General Comments

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