INT72640

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Context Info
Confidence 0.13
First Reported 1997
Last Reported 1997
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0.30

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signal transduction (Ntsr1) extracellular region (Nts) plasma membrane (Ntsr1)
signal transducer activity (Ntsr1)
Ntsr1 (Mus musculus)
Nts (Mus musculus)
Pain Link Frequency Relevance Heat
Nucleus accumbens 1 98.88 Very High Very High Very High
agonist 3 95.24 Very High Very High Very High
Dopamine 1 91.84 High High
Analgesic 3 91.16 High High
Eae 1 56.48 Quite High
analgesia 1 36.32 Quite Low
narcan 1 26.80 Quite Low
Disease Link Frequency Relevance Heat
Catalepsy 1 67.12 Quite High
Hypothermia 1 33.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study, the effects of neurotensin and NT1 (N alpha Me-Arg-Lys-Pro-Trp-TIe-Leu or Eisai hexapeptide), a metabolically stable and systemically active neurotensin agonist, were examined in several models of antipsychotic activity and side effect liability in mice; analgesic and hypothermic effects of both compounds also were determined.
NT1 Spec (examined) Regulation (effects) of neurotensin associated with analgesic and agonist
1) Confidence 0.13 Published 1997 Journal Peptides Section Abstract Doc Link 9396065 Disease Relevance 0.07 Pain Relevance 0.30

General Comments

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