INT72666

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Context Info
Confidence 0.03
First Reported 1997
Last Reported 1997
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.53
Pain Relevance 1.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transducer activity (Oprm1)
ODT (Homo sapiens)
Oprm1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
opioid receptor 2 100.00 Very High Very High Very High
Analgesic 4 99.24 Very High Very High Very High
tramadol 11 99.02 Very High Very High Very High
Potency 1 98.84 Very High Very High Very High
Serotonin 1 96.52 Very High Very High Very High
Osteoarthritis 1 90.08 High High
Lasting pain 1 88.80 High High
Pain 1 88.16 High High
cINOD 1 84.32 Quite High
opiate 1 82.32 Quite High
Disease Link Frequency Relevance Heat
Osteoarthritis 1 90.08 High High
Pain 2 88.80 High High
INFLAMMATION 1 84.12 Quite High
Hypersensitivity 1 63.20 Quite High
Convulsion 1 61.28 Quite High
Adverse Drug Reaction 1 58.96 Quite High
Poisoning 1 25.00 Low Low
Toxicity 1 25.00 Low Low
Overdose 2 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Tramadol's major active metabolite, O-desmethyltramadol (ODT), shows higher affinity for the mu-opioid receptor and has twice the analgesic potency of the parent drug.
ODT Binding (affinity) of mu-opioid receptor associated with tramadol, analgesic, opioid receptor and potency
1) Confidence 0.03 Published 1997 Journal J Anal Toxicol Section Abstract Doc Link 9399121 Disease Relevance 0.53 Pain Relevance 1.50

General Comments

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