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Context Info
Confidence 0.69
First Reported 1997
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.27
Pain Relevance 1.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (SI) aging (SI) Golgi apparatus (SI)
plasma membrane (SI) carbohydrate metabolic process (SI)
Anatomy Link Frequency
brush 1
SI (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 18 99.32 Very High Very High Very High
aspirin 8 90.96 High High
nud 1 84.96 Quite High
cINOD 1 54.52 Quite High
Disease Link Frequency Relevance Heat
Pain 13 99.32 Very High Very High Very High
Cognitive Disorder 1 99.32 Very High Very High Very High
Disorder Of Lipid Metabolism 1 98.48 Very High Very High Very High
Giardiasis 7 96.44 Very High Very High Very High
Apoptosis 2 92.84 High High
Dyspepsia 1 84.96 Quite High
Nociception 3 76.00 Quite High
Colon Cancer 4 75.00 Quite High
Familial Adenomatous Polyposis 2 65.52 Quite High
Cancer 1 62.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The inhibition of growth is associated with a dose-dependent reduction in insulin-like growth factor II mRNA expression and with an increase in sucrase activity (a brush border enzyme) and apolipoprotein A-I mRNA expression, 2 specific markers of the differentiative status of this cell line.
Positive_regulation (increase) of sucrase in brush associated with disorder of lipid metabolism
1) Confidence 0.69 Published 1997 Journal Int. J. Cancer Section Abstract Doc Link 9399670 Disease Relevance 0.76 Pain Relevance 0.32
Recent studies more specifically implicate SI in the sensory aspect of pain perception by demonstrating that SI activation is modulated by cognitive manipulations that alter perceived pain intensity, but not by manipulations that alter unpleasantness, independent of pain intensity.
Positive_regulation (activation) of SI associated with pain and cognitive disorder
2) Confidence 0.59 Published 2003 Journal Adv Neurol Section Abstract Doc Link 12894402 Disease Relevance 0.77 Pain Relevance 0.75
Estimation of lactase, sucrase, maltase and trehalase was done in biopsies.
Positive_regulation (Estimation) of sucrase
3) Confidence 0.01 Published 2000 Journal Trop Gastroenterol Section Abstract Doc Link 11194577 Disease Relevance 0.75 Pain Relevance 0.13

General Comments

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