INT7293

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Context Info
Confidence 0.43
First Reported 1988
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 1.40
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Nppa) nucleus (Nppa) cytoplasm (Nppa)
Anatomy Link Frequency
renal nerve 4
Nppa (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Somatostatin 1 98.80 Very High Very High Very High
Enkephalin 1 94.12 High High
c fibre 10 89.76 High High
Potency 1 85.84 High High
antagonist 2 75.00 Quite High
Neurotransmitter 1 26.40 Quite Low
anesthesia 1 25.00 Low Low
imagery 11 17.68 Low Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Natriuresis 14 100.00 Very High Very High Very High
Papilloma 52 99.52 Very High Very High Very High
Intraductal Papilloma 18 72.48 Quite High
Thyroid Neoplasm 1 57.32 Quite High
Malignant Neoplastic Disease 19 51.80 Quite High
Cancer 12 47.24 Quite Low
Hypotension 1 33.92 Quite Low
Pressure Volume 2 Under Development 2 25.00 Low Low
Breast Cancer 6 12.16 Low Low
Calcification 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Administration of atrial natriuretic factor (ANF) to anesthetized rats decreases renal nerve activity (RNA), an effect prevented by vagotomy but not by atropine.
Negative_regulation (decreases) of atrial natriuretic factor Binding (Administration) of in renal nerve associated with natriuresis
1) Confidence 0.43 Published 1988 Journal Am. J. Physiol. Section Abstract Doc Link 2969196 Disease Relevance 0.17 Pain Relevance 0.16
Administration of atrial natriuretic factor (ANF) to anesthetized rats decreases renal nerve activity (RNA), an effect prevented by vagotomy but not by atropine.
Negative_regulation (decreases) of ANF Binding (Administration) of in renal nerve associated with natriuresis
2) Confidence 0.43 Published 1988 Journal Am. J. Physiol. Section Abstract Doc Link 2969196 Disease Relevance 0.17 Pain Relevance 0.16
The 125I-ANF binding to retinal particulate preparations was not inhibited by 1 microM concentration of somatostatin, vasopressin, vasoactive intestinal peptide, adrenocorticotropin, thyrotropin releasing hormone, or leu-enkephalin.
Negative_regulation (inhibited) of ANF Binding (binding) of associated with somatostatin and enkephalin
3) Confidence 0.40 Published 1989 Journal Life Sci. Section Abstract Doc Link 2544774 Disease Relevance 0.23 Pain Relevance 0.19
MD has recently revolutionised the management of PND and breast papillomas.
Negative_regulation (revolutionised) of PND Binding (management) of associated with papilloma
4) Confidence 0.34 Published 2006 Journal Int Semin Surg Oncol Section Body Doc Link PMC1395317 Disease Relevance 0.41 Pain Relevance 0
HS-142-1, a novel polysaccharide, isolated from the culture broth of Aureobasidium pullulans var. melanigenum, has been found to inhibit selectively the binding of [125I]atrial natriuretic peptide (ANP) to the guanylyl cyclase-linked ANP receptor (ANP-B receptor) and production of cyclic GMP by ANP.
Negative_regulation (inhibit) of atrial natriuretic peptide Binding (binding) of associated with natriuresis
5) Confidence 0.15 Published 1992 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 1346647 Disease Relevance 0.41 Pain Relevance 0.04

General Comments

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